De Leenheer E - Search Results

1

Peripheral Proinsulin Expression Controls Low-Avidity Proinsulin-Reactive CD8 T Cells in Type 1 Diabetes.

Thayer TC, Pearson JA, De Leenheer E, Hanna SJ, Boldison J, Davies J, Tsui A, Ahmed S, Easton P, Siew LK, Wen L, Wong FS. Thayer TC, et al. Among authors: de leenheer e. Diabetes. 2016 Nov;65(11):3429-3439. doi: 10.2337/db15-1649. Epub 2016 Aug 5. Diabetes. 2016. PMID: 27495224

2

A reproducible method for the expansion of mouse CD8+ T lymphocytes.

Lewis MD, de Leenheer E, Fishman S, Siew LK, Gross G, Wong FS. Lewis MD, et al. Among authors: de leenheer e. J Immunol Methods. 2015 Feb;417:134-138. doi: 10.1016/j.jim.2015.01.004. Epub 2015 Jan 17. J Immunol Methods. 2015. PMID: 25602136 Free PMC article.

3

Adoptive Transfer of Autoimmune Diabetes Using Immunodeficient Nonobese Diabetic (NOD) Mice.

De Leenheer E, Wong FS. De Leenheer E, et al. Methods Mol Biol. 2016;1433:135-40. doi: 10.1007/7651_2015_294. Methods Mol Biol. 2016. PMID: 26791362

4

Proinsulin Expression Shapes the TCR Repertoire but Fails to Control the Development of Low-Avidity Insulin-Reactive CD8+ T Cells.

Pearson JA, Thayer TC, McLaren JE, Ladell K, De Leenheer E, Phillips A, Davies J, Kakabadse D, Miners K, Morgan P, Wen L, Price DA, Wong FS. Pearson JA, et al. Among authors: de leenheer e. Diabetes. 2016 Jun;65(6):1679-89. doi: 10.2337/db15-1498. Epub 2016 Mar 7. Diabetes. 2016. PMID: 26953160 Free PMC article.

5

B cell depletion reduces T cell activation in pancreatic islets in a murine autoimmune diabetes model.

Da Rosa LC, Boldison J, De Leenheer E, Davies J, Wen L, Wong FS. Da Rosa LC, et al. Among authors: de leenheer e. Diabetologia. 2018 Jun;61(6):1397-1410. doi: 10.1007/s00125-018-4597-z. Epub 2018 Mar 28. Diabetologia. 2018. PMID: 29594371 Free PMC article.

6

Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.

Motozono C, Pearson JA, De Leenheer E, Rizkallah PJ, Beck K, Trimby A, Sewell AK, Wong FS, Cole DK. Motozono C, et al. Among authors: de leenheer e. J Biol Chem. 2015 Jul 31;290(31):18924-33. doi: 10.1074/jbc.M114.622522. Epub 2015 Jun 17. J Biol Chem. 2015. PMID: 26085090 Free PMC article.

7

Adoptive Transfer of mRNA-Transfected T Cells Redirected against Diabetogenic CD8 T Cells Can Prevent Diabetes.

Fishman S, Lewis MD, Siew LK, De Leenheer E, Kakabadse D, Davies J, Ziv D, Margalit A, Karin N, Gross G, Wong FS. Fishman S, et al. Among authors: de leenheer e. Mol Ther. 2017 Feb 1;25(2):456-464. doi: 10.1016/j.ymthe.2016.12.007. Epub 2017 Jan 18. Mol Ther. 2017. PMID: 28109957 Free PMC article.

8

Conjugation of lymphoma idiotype to CD40 antibody enhances lymphoma vaccine immunogenicity and antitumor effects in mice.

Carlring J, Szabo MJ, Dickinson R, De Leenheer E, Heath AW. Carlring J, et al. Among authors: de leenheer e. Blood. 2012 Mar 1;119(9):2056-65. doi: 10.1182/blood-2011-05-355461. Epub 2012 Jan 10. Blood. 2012. PMID: 22234700 Free article.

9

CD40mAb adjuvant induces a rapid antibody response that may be beneficial in post-exposure prophylaxis.

Bhagawati-Prasad VN, De Leenheer E, Keefe NP, Ryan LA, Carlring J, Heath AW. Bhagawati-Prasad VN, et al. Among authors: de leenheer e. J Immune Based Ther Vaccines. 2010 Feb 4;8:1. doi: 10.1186/1476-8518-8-1. J Immune Based Ther Vaccines. 2010. PMID: 20205811 Free PMC article.

10

A novel redox method for rapid production of functional bi-specific antibodies for use in early pilot studies.

Carlring J, De Leenheer E, Heath AW. Carlring J, et al. Among authors: de leenheer e. PLoS One. 2011;6(7):e22533. doi: 10.1371/journal.pone.0022533. Epub 2011 Jul 21. PLoS One. 2011. PMID: 21811628 Free PMC article.

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