Bisson WH - Search Results

1

Divergent Ah Receptor Ligand Selectivity during Hominin Evolution.

Hubbard TD, Murray IA, Bisson WH, Sullivan AP, Sebastian A, Perry GH, Jablonski NG, Perdew GH. Hubbard TD, et al. Among authors: bisson wh. Mol Biol Evol. 2016 Oct;33(10):2648-58. doi: 10.1093/molbev/msw143. Epub 2016 Aug 2. Mol Biol Evol. 2016. PMID: 27486223 Free PMC article.

2

Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-α-naphthoflavone.

Murray IA, Flaveny CA, Chiaro CR, Sharma AK, Tanos RS, Schroeder JC, Amin SG, Bisson WH, Kolluri SK, Perdew GH. Murray IA, et al. Among authors: bisson wh. Mol Pharmacol. 2011 Mar;79(3):508-19. doi: 10.1124/mol.110.069369. Epub 2010 Dec 2. Mol Pharmacol. 2011. PMID: 21127131 Free PMC article.

3

Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles.

Hubbard TD, Murray IA, Bisson WH, Lahoti TS, Gowda K, Amin SG, Patterson AD, Perdew GH. Hubbard TD, et al. Among authors: bisson wh. Sci Rep. 2015 Aug 3;5:12689. doi: 10.1038/srep12689. Sci Rep. 2015. PMID: 26235394 Free PMC article.

4

Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism.

Smith KJ, Murray IA, Tanos R, Tellew J, Boitano AE, Bisson WH, Kolluri SK, Cooke MP, Perdew GH. Smith KJ, et al. Among authors: bisson wh. J Pharmacol Exp Ther. 2011 Jul;338(1):318-27. doi: 10.1124/jpet.110.178392. Epub 2011 Apr 14. J Pharmacol Exp Ther. 2011. PMID: 21493753 Free PMC article.

5

A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain.

Perkins A, Phillips JL, Kerkvliet NI, Tanguay RL, Perdew GH, Kolluri SK, Bisson WH. Perkins A, et al. Among authors: bisson wh. Biology (Basel). 2014 Oct 17;3(4):645-69. doi: 10.3390/biology3040645. Biology (Basel). 2014. PMID: 25329374 Free PMC article.

6

Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs.

Goodale BC, La Du J, Tilton SC, Sullivan CM, Bisson WH, Waters KM, Tanguay RL. Goodale BC, et al. Among authors: bisson wh. Toxicol Sci. 2015 Oct;147(2):397-411. doi: 10.1093/toxsci/kfv139. Epub 2015 Jul 3. Toxicol Sci. 2015. PMID: 26141390 Free PMC article.

7

Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands.

Bisson WH, Koch DC, O'Donnell EF, Khalil SM, Kerkvliet NI, Tanguay RL, Abagyan R, Kolluri SK. Bisson WH, et al. J Med Chem. 2009 Sep 24;52(18):5635-41. doi: 10.1021/jm900199u. J Med Chem. 2009. PMID: 19719119 Free PMC article.

8

Mechanistic Investigations Into the Developmental Toxicity of Nitrated and Heterocyclic PAHs.

Chlebowski AC, Garcia GR, La Du JK, Bisson WH, Truong L, Massey Simonich SL, Tanguay RL. Chlebowski AC, et al. Among authors: bisson wh. Toxicol Sci. 2017 May 1;157(1):246-259. doi: 10.1093/toxsci/kfx035. Toxicol Sci. 2017. PMID: 28186253 Free PMC article.

9

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor.

O'Donnell EF, Saili KS, Koch DC, Kopparapu PR, Farrer D, Bisson WH, Mathew LK, Sengupta S, Kerkvliet NI, Tanguay RL, Kolluri SK. O'Donnell EF, et al. Among authors: bisson wh. PLoS One. 2010 Oct 1;5(10):e13128. doi: 10.1371/journal.pone.0013128. PLoS One. 2010. PMID: 20957046 Free PMC article.

10

Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells.

Jang HS, Pearce M, O'Donnell EF, Nguyen BD, Truong L, Mueller MJ, Bisson WH, Kerkvliet NI, Tanguay RL, Kolluri SK. Jang HS, et al. Among authors: bisson wh. Biology (Basel). 2017 Dec 1;6(4):41. doi: 10.3390/biology6040041. Biology (Basel). 2017. PMID: 29194351 Free PMC article.

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