Chua L - Search Results

1

Duration of action of two insulin glargine products, LY2963016 insulin glargine and Lantus insulin glargine, in subjects with type 1 diabetes mellitus.

Linnebjerg H, Lam EC, Zhang X, Seger ME, Coutant D, Chua L, Kapitza C, Heise T. Linnebjerg H, et al. Among authors: chua l. Diabetes Obes Metab. 2017 Jan;19(1):33-39. doi: 10.1111/dom.12759. Epub 2016 Sep 8. Diabetes Obes Metab. 2017. PMID: 27484286 Free PMC article. Clinical Trial.

2

Comparison of the Pharmacokinetics and Pharmacodynamics of LY2963016 Insulin Glargine and EU- and US-Approved Versions of Lantus Insulin Glargine in Healthy Subjects: Three Randomized Euglycemic Clamp Studies.

Linnebjerg H, Lam EC, Seger ME, Coutant D, Chua L, Chong CL, Ferreira MM, Soon D, Zhang X. Linnebjerg H, et al. Among authors: chua l. Diabetes Care. 2015 Dec;38(12):2226-33. doi: 10.2337/dc14-2623. Epub 2015 Aug 25. Diabetes Care. 2015. PMID: 26307603 Clinical Trial.

3

Dose/Exposure-Response Modeling to Support Dosing Recommendation for Phase III Development of Baricitinib in Patients with Rheumatoid Arthritis.

Zhang X, Chua L, Ernest C 2nd, Macias W, Rooney T, Tham LS. Zhang X, et al. Among authors: chua l. CPT Pharmacometrics Syst Pharmacol. 2017 Dec;6(12):804-813. doi: 10.1002/psp4.12251. Epub 2017 Oct 17. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 28891251 Free PMC article. Clinical Trial.

4

LY2963016 Insulin Glargine and Insulin Glargine (Lantus) Produce Comparable Pharmacokinetics and Pharmacodynamics at Two Dose Levels.

Zhang X, Lam ECQ, Seger ME, Coutant D, Chua L, Tan LH, Soon D, Linnebjerg H. Zhang X, et al. Among authors: chua l. Clin Pharmacol Drug Dev. 2017 Nov;6(6):556-563. doi: 10.1002/cpdd.392. Epub 2017 Sep 21. Clin Pharmacol Drug Dev. 2017. PMID: 28940840 Clinical Trial.

5

A Euglycemic Glucose Clamp Study to Evaluate the Bioavailability of LY2963016 Relative to Insulin Glargine in Healthy Chinese Subjects.

Liu H, Wang F, Ji Y, Ma T, Li H, Linnebjerg H, Chua L, Tham LS, Yu Y. Liu H, et al. Among authors: chua l. Clin Pharmacol Drug Dev. 2021 Dec;10(12):1452-1459. doi: 10.1002/cpdd.1014. Epub 2021 Aug 19. Clin Pharmacol Drug Dev. 2021. PMID: 34410042 Clinical Trial.

6

Mirikizumab Pharmacokinetics in Patients with Moderately to Severely Active Ulcerative Colitis: Results from Phase III LUCENT Studies.

Chua L, Friedrich S, Zhang XC. Chua L, et al. Clin Pharmacokinet. 2023 Oct;62(10):1479-1491. doi: 10.1007/s40262-023-01281-z. Epub 2023 Aug 23. Clin Pharmacokinet. 2023. PMID: 37610533 Free PMC article.

7

Mirikizumab Exposure-Response Relationships in Patients with Moderately-to-Severely Active Ulcerative Colitis in Randomized Phase II and III Studies.

Friedrich S, Chua L, Adams DH, Crandall W, Zhang XC. Friedrich S, et al. Among authors: chua l. Clin Pharmacol Ther. 2024 Aug;116(2):435-447. doi: 10.1002/cpt.3305. Epub 2024 May 26. Clin Pharmacol Ther. 2024. PMID: 38797892 Clinical Trial.

8

Mirikizumab pharmacokinetics and exposure-response in pediatric patients with moderate-to-severe ulcerative colitis.

Otani Y, Chua L, Komocsar WJ, Larkin A, Johns J, Zhang X. Otani Y, et al. Among authors: chua l. CPT Pharmacometrics Syst Pharmacol. 2024 Dec 18. doi: 10.1002/psp4.13286. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 39693227 Free article.

9

Ixekizumab Pharmacokinetics, Anti-Drug Antibodies, and Efficacy through 60 Weeks of Treatment of Moderate to Severe Plaque Psoriasis.

Reich K, Jackson K, Ball S, Garces S, Kerr L, Chua L, Muram TM, Blauvelt A. Reich K, et al. Among authors: chua l. J Invest Dermatol. 2018 Oct;138(10):2168-2173. doi: 10.1016/j.jid.2018.04.019. Epub 2018 May 8. J Invest Dermatol. 2018. PMID: 29751001 Free article. Clinical Trial.

10

Population pharmacokinetic and exposure-efficacy analysis of ixekizumab in paediatric patients with moderate-to-severe plaque psoriasis (IXORA-PEDS).

Jackson K, Chua L, Velez de Mendizabal N, Pitou C, Rodriguez Capriles C, Paller AS, Lansang P, Seyger MMB, Papp K; IXORA-PEDS study group. Jackson K, et al. Among authors: chua l. Br J Clin Pharmacol. 2022 Mar;88(3):1074-1086. doi: 10.1111/bcp.15034. Epub 2021 Sep 2. Br J Clin Pharmacol. 2022. PMID: 34378230 Free PMC article.

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