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The aged lymphoid tissue environment fails to support naïve T cell homeostasis.
Becklund BR, Purton JF, Ramsey C, Favre S, Vogt TK, Martin CE, Spasova DS, Sarkisyan G, LeRoy E, Tan JT, Wahlus H, Bondi-Boyd B, Luther SA, Surh CD. Becklund BR, et al. Among authors: sarkisyan g. Sci Rep. 2016 Aug 2;6:30842. doi: 10.1038/srep30842. Sci Rep. 2016. PMID: 27480406 Free PMC article.
Sphingosine-1-phosphate receptor-1 (S1P1) is expressed by lymphocytes, dendritic cells, and endothelium and modulated during inflammatory bowel disease.
Karuppuchamy T, Behrens EH, González-Cabrera P, Sarkisyan G, Gima L, Boyer JD, Bamias G, Jedlicka P, Veny M, Clark D, Peach R, Scott F, Rosen H, Rivera-Nieves J. Karuppuchamy T, et al. Among authors: sarkisyan g. Mucosal Immunol. 2017 Jan;10(1):162-171. doi: 10.1038/mi.2016.35. Epub 2016 Apr 6. Mucosal Immunol. 2017. PMID: 27049060 Free PMC article.
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor.
Hedlund PB, Leopoldo M, Caccia S, Sarkisyan G, Fracasso C, Martelli G, Lacivita E, Berardi F, Perrone R. Hedlund PB, et al. Among authors: sarkisyan g. Neurosci Lett. 2010 Aug 30;481(1):12-6. doi: 10.1016/j.neulet.2010.06.036. Epub 2010 Jun 23. Neurosci Lett. 2010. PMID: 20600619 Free PMC article.
Actions of a picomolar short-acting S1P₁ agonist in S1P₁-eGFP knock-in mice.
Cahalan SM, Gonzalez-Cabrera PJ, Sarkisyan G, Nguyen N, Schaeffer MT, Huang L, Yeager A, Clemons B, Scott F, Rosen H. Cahalan SM, et al. Among authors: sarkisyan g. Nat Chem Biol. 2011 May;7(5):254-6. doi: 10.1038/nchembio.547. Epub 2011 Mar 27. Nat Chem Biol. 2011. PMID: 21445057 Free PMC article.
28 results