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Page 1
E2f8 mediates tumor suppression in postnatal liver development.
Kent LN, Rakijas JB, Pandit SK, Westendorp B, Chen HZ, Huntington JT, Tang X, Bae S, Srivastava A, Senapati S, Koivisto C, Martin CK, Cuitino MC, Perez M, Clouse JM, Chokshi V, Shinde N, Kladney R, Sun D, Perez-Castro A, Matondo RB, Nantasanti S, Mokry M, Huang K, Machiraju R, Fernandez S, Rosol TJ, Coppola V, Pohar KS, Pipas JM, Schmidt CR, de Bruin A, Leone G. Kent LN, et al. Among authors: de bruin a. J Clin Invest. 2016 Aug 1;126(8):2955-69. doi: 10.1172/JCI85506. Epub 2016 Jul 25. J Clin Invest. 2016. PMID: 27454291 Free PMC article.
Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.
Kent LN, Bae S, Tsai SY, Tang X, Srivastava A, Koivisto C, Martin CK, Ridolfi E, Miller GC, Zorko SM, Plevris E, Hadjiyannis Y, Perez M, Nolan E, Kladney R, Westendorp B, de Bruin A, Fernandez S, Rosol TJ, Pohar KS, Pipas JM, Leone G. Kent LN, et al. Among authors: de bruin a. J Clin Invest. 2017 Mar 1;127(3):830-842. doi: 10.1172/JCI87583. Epub 2017 Jan 30. J Clin Invest. 2017. PMID: 28134624 Free PMC article.
E2F8 is essential for polyploidization in mammalian cells.
Pandit SK, Westendorp B, Nantasanti S, van Liere E, Tooten PC, Cornelissen PW, Toussaint MJ, Lamers WH, de Bruin A. Pandit SK, et al. Among authors: de bruin a. Nat Cell Biol. 2012 Nov;14(11):1181-91. doi: 10.1038/ncb2585. Epub 2012 Oct 14. Nat Cell Biol. 2012. PMID: 23064264
Atypical E2F repressors and activators coordinate placental development.
Ouseph MM, Li J, Chen HZ, Pécot T, Wenzel P, Thompson JC, Comstock G, Chokshi V, Byrne M, Forde B, Chong JL, Huang K, Machiraju R, de Bruin A, Leone G. Ouseph MM, et al. Among authors: de bruin a. Dev Cell. 2012 Apr 17;22(4):849-62. doi: 10.1016/j.devcel.2012.01.013. Dev Cell. 2012. PMID: 22516201 Free PMC article.
HIF proteins connect the RB-E2F factors to angiogenesis.
Bakker WJ, Weijts BG, Westendorp B, de Bruin A. Bakker WJ, et al. Among authors: de bruin a. Transcription. 2013 Mar-Apr;4(2):62-6. doi: 10.4161/trns.23680. Epub 2013 Feb 14. Transcription. 2013. PMID: 23412359 Free PMC article.
392 results