O'Hagan DT - Search Results

1

Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines.

Buonsanti C, Balocchi C, Harfouche C, Corrente F, Galli Stampino L, Mancini F, Tontini M, Malyala P, Bufali S, Baudner B, De Gregorio E, Valiante NM, O'Hagan DT, Rappuoli R, D'Oro U. Buonsanti C, et al. Sci Rep. 2016 Jul 21;6:29063. doi: 10.1038/srep29063. Sci Rep. 2016. PMID: 27439378 Free PMC article.

2

The preparation and characterization of PLG nanoparticles with an entrapped synthetic TLR7 agonist and their preclinical evaluation as adjuvant for an adsorbed DTaP vaccine.

Bruno C, Agnolon V, Berti F, Bufali S, O'Hagan DT, Baudner BC. Bruno C, et al. Eur J Pharm Biopharm. 2016 Aug;105:1-8. doi: 10.1016/j.ejpb.2016.05.013. Epub 2016 May 17. Eur J Pharm Biopharm. 2016. PMID: 27224856

3

The adjuvant effect of TLR7 agonist conjugated to a meningococcal serogroup C glycoconjugate vaccine.

Donadei A, Balocchi C, Mancini F, Proietti D, Gallorini S, O'Hagan DT, D'Oro U, Berti F, Baudner BC, Adamo R. Donadei A, et al. Eur J Pharm Biopharm. 2016 Oct;107:110-9. doi: 10.1016/j.ejpb.2016.07.004. Epub 2016 Jul 5. Eur J Pharm Biopharm. 2016. PMID: 27388628

4

Conjugation of a TLR7 agonist and antigen enhances protection in the S. pneumoniae murine infection model.

Vecchi S, Bufali S, Uno T, Wu T, Arcidiacono L, Filippini S, Rigat F, O'Hagan D. Vecchi S, et al. Eur J Pharm Biopharm. 2014 Jul;87(2):310-7. doi: 10.1016/j.ejpb.2014.01.002. Epub 2014 Jan 14. Eur J Pharm Biopharm. 2014. PMID: 24434202

5

Gaps in knowledge and prospects for research of adjuvanted vaccines.

Seder R, Reed SG, O'Hagan D, Malyala P, D'Oro U, Laera D, Abrignani S, Cerundolo V, Steinman L, Bertholet S. Seder R, et al. Vaccine. 2015 Jun 8;33 Suppl 2:B40-3. doi: 10.1016/j.vaccine.2015.03.057. Vaccine. 2015. PMID: 26022566

6

Recent advances in the discovery and delivery of vaccine adjuvants.

O'Hagan DT, Valiante NM. O'Hagan DT, et al. Nat Rev Drug Discov. 2003 Sep;2(9):727-35. doi: 10.1038/nrd1176. Nat Rev Drug Discov. 2003. PMID: 12951579 Free PMC article. Review.

7

Novel approaches to vaccine delivery.

O'Hagan DT, Rappuoli R. O'Hagan DT, et al. Pharm Res. 2004 Sep;21(9):1519-30. doi: 10.1023/b:pham.0000041443.17935.33. Pharm Res. 2004. PMID: 15497674 Free PMC article. Review.

8

Novel approaches to pediatric vaccine delivery.

O'Hagan DT, Rappuoli R. O'Hagan DT, et al. Adv Drug Deliv Rev. 2006 Apr 20;58(1):29-51. doi: 10.1016/j.addr.2005.12.002. Epub 2006 Feb 9. Adv Drug Deliv Rev. 2006. PMID: 16480788 Review.

9

The path to a successful vaccine adjuvant--'the long and winding road'.

O'Hagan DT, De Gregorio E. O'Hagan DT, et al. Drug Discov Today. 2009 Jun;14(11-12):541-51. doi: 10.1016/j.drudis.2009.02.009. Epub 2009 Mar 5. Drug Discov Today. 2009. PMID: 19508916 Review.

10

Bioadhesive delivery systems for mucosal vaccine delivery.

Baudner BC, O'Hagan DT. Baudner BC, et al. J Drug Target. 2010 Dec;18(10):752-70. doi: 10.3109/1061186X.2010.529143. Epub 2010 Nov 2. J Drug Target. 2010. PMID: 21039314 Review.

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