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Propargyl-linked antifolates are dual inhibitors of Candida albicans and Candida glabrata.
G-Dayanandan N, Paulsen JL, Viswanathan K, Keshipeddy S, Lombardo MN, Zhou W, Lamb KM, Sochia AE, Alverson JB, Priestley ND, Wright DL, Anderson AC. G-Dayanandan N, et al. Among authors: keshipeddy s. J Med Chem. 2014 Mar 27;57(6):2643-56. doi: 10.1021/jm401916j. Epub 2014 Mar 6. J Med Chem. 2014. PMID: 24568657 Free PMC article.
MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.
Reeve SM, Scocchera EW, G-Dayanadan N, Keshipeddy S, Krucinska J, Hajian B, Ferreira J, Nailor M, Aeschlimann J, Wright DL, Anderson AC. Reeve SM, et al. Among authors: keshipeddy s. Cell Chem Biol. 2016 Dec 22;23(12):1458-1467. doi: 10.1016/j.chembiol.2016.11.007. Epub 2016 Dec 8. Cell Chem Biol. 2016. PMID: 27939900 Free PMC article.
Pharmaceutical analysis of a novel propargyl-linked antifolate antibiotic in the mouse.
Hoody J, Alverson JB, Keshipeddy S, Barney PA, Walker L, Anderson AC, Wright DL, Priestley ND. Hoody J, et al. Among authors: keshipeddy s. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Apr 15;1051:54-59. doi: 10.1016/j.jchromb.2017.02.026. Epub 2017 Mar 6. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 28314188 Free PMC article.
Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound.
Bond MJ, Bleiler M, Harrison LE, Scocchera EW, Nakanishi M, G-Dayanan N, Keshipeddy S, Rosenberg DW, Wright DL, Giardina C. Bond MJ, et al. Among authors: keshipeddy s. Mol Cancer Res. 2018 Sep;16(9):1361-1372. doi: 10.1158/1541-7786.MCR-18-0178. Epub 2018 May 16. Mol Cancer Res. 2018. PMID: 29769406 Free PMC article.
27 results