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Page 1
The Renal Outer Medullary Potassium Channel Inhibitor, MK-7145, Lowers Blood Pressure, and Manifests Features of Bartter's Syndrome Type II Phenotype.
Hampton C, Zhou X, Priest BT, Pai LY, Felix JP, Thomas-Fowlkes B, Liu J, Kohler M, Xiao J, Corona A, Price O, Gill C, Shah K, Rasa C, Tong V, Owens K, Ormes J, Tang H, Roy S, Sullivan KA, Metzger JM, Alonso-Galicia M, Kaczorowski GJ, Pasternak A, Garcia ML. Hampton C, et al. Among authors: corona a. J Pharmacol Exp Ther. 2016 Oct;359(1):194-206. doi: 10.1124/jpet.116.235150. Epub 2016 Jul 18. J Pharmacol Exp Ther. 2016. PMID: 27432892
The design and synthesis of novel spirocyclic heterocyclic sulfone ROMK inhibitors as diuretics.
Chobanian HR, Guo Y, Pio B, Tang H, Teumelsan N, Clements M, Frie J, Ferguson R, Guo Z, Thomas-Fowlkes BS, Felix JP, Liu J, Kohler M, Priest B, Hampton C, Pai LY, Corona A, Metzger J, Tong V, Joshi EM, Xu L, Owens K, Maloney K, Sullivan K, Pasternak A. Chobanian HR, et al. Among authors: corona a. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1109-1114. doi: 10.1016/j.bmcl.2016.10.032. Epub 2016 Oct 13. Bioorg Med Chem Lett. 2017. PMID: 28111141
Discovery of a Potent and Selective ROMK Inhibitor with Pharmacokinetic Properties Suitable for Preclinical Evaluation.
Walsh SP, Shahripour A, Tang H, Teumelsan N, Frie J, Zhu Y, Priest BT, Swensen AM, Liu J, Margulis M, Visconti R, Weinglass A, Felix JP, Brochu RM, Bailey T, Thomas-Fowlkes B, Alonso-Galicia M, Zhou X, Pai LY, Corona A, Hampton C, Hernandez M, Bentley R, Chen J, Shah K, Metzger J, Forrest M, Owens K, Tong V, Ha S, Roy S, Kaczorowski GJ, Yang L, Parmee E, Garcia ML, Sullivan K, Pasternak A. Walsh SP, et al. Among authors: corona a. ACS Med Chem Lett. 2015 May 7;6(7):747-52. doi: 10.1021/ml500440u. eCollection 2015 Jul 9. ACS Med Chem Lett. 2015. PMID: 26191360 Free PMC article.
Discovery of MK-7145, an Oral Small Molecule ROMK Inhibitor for the Treatment of Hypertension and Heart Failure.
Tang H, Zhu Y, Teumelsan N, Walsh SP, Shahripour A, Priest BT, Swensen AM, Felix JP, Brochu RM, Bailey T, Thomas-Fowlkes B, Pai LY, Hampton C, Corona A, Hernandez M, Metzger J, Forrest M, Zhou X, Owens K, Tong V, Parmee E, Roy S, Kaczorowski GJ, Yang L, Alonso-Galicia M, Garcia ML, Pasternak A. Tang H, et al. Among authors: corona a. ACS Med Chem Lett. 2016 May 12;7(7):697-701. doi: 10.1021/acsmedchemlett.6b00122. eCollection 2016 Jul 14. ACS Med Chem Lett. 2016. PMID: 27437080 Free PMC article.
Thiol-Reactive or Redox-Active: Revising a Repurposing Screen Led to a New Invalidation Pipeline and Identified a True Noncovalent Inhibitor Against Papain-like Protease from SARS-CoV-2.
Kuzikov M, Morasso S, Reinshagen J, Wolf M, Monaco V, Cozzolino F, Golič Grdadolnik S, Šket P, Plavec J, Iaconis D, Summa V, Corona A, Paulis A, Esposito F, Tramontano E, Monti M, Beccari AR, Manelfi C, Windshügel B, Gribbon P, Storici P, Zaliani A. Kuzikov M, et al. Among authors: corona a. ACS Pharmacol Transl Sci. 2024 Oct 4;8(1):66-77. doi: 10.1021/acsptsci.4c00325. eCollection 2025 Jan 10. ACS Pharmacol Transl Sci. 2024. PMID: 39816795
Structure-based discovery of novel diarylpyrimidines as potent and selective Non-Nucleoside reverse transcriptase inhibitors: From CH(CN)-Biphenyl-Diarylpyrimidines to CNNH2-Biphenyl-Diarylpyrimidines.
Chen XM, Pannecouque C, De Clercq E, Lian YX, Corona A, Dettori L, Tramontano E, Wang S, Chen FE. Chen XM, et al. Among authors: corona a. Eur J Med Chem. 2025 Mar 5;285:117271. doi: 10.1016/j.ejmech.2025.117271. Epub 2025 Jan 12. Eur J Med Chem. 2025. PMID: 39813776
Effects of Chlorpyrifos on gut dysbiosis and barriers integrity in women with a focus on pregnancy and prebiotic intervention: Insights from advanced in vitro human models.
Abou Diwan M, Huet A, Poiriez J, Joly Condette C, Delanaud S, Sevin E, Corona A, Rhazi L, Depeint F, Ouadid-Ahidouch H, Gosselet F, Bach V, Candela P, Khorsi-Cauet H. Abou Diwan M, et al. Among authors: corona a. Environ Pollut. 2024 Dec 13;367:125533. doi: 10.1016/j.envpol.2024.125533. Online ahead of print. Environ Pollut. 2024. PMID: 39674256 Free article.
Dynamic CRRT Prescription for Complicated Critically Ill Patient: A Case Report.
Santorsola C, Corona A, Cecchi M, Nicolini NC, Zendra E, Capone A, Gatti I, Brivio M, Falsini S, Villa G. Santorsola C, et al. Among authors: corona a. Case Rep Crit Care. 2024 Nov 20;2024:1837150. doi: 10.1155/2024/1837150. eCollection 2024. Case Rep Crit Care. 2024. PMID: 39611098 Free PMC article.
349 results