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Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo.
Spiess K, Jeppesen MG, Malmgaard-Clausen M, Krzywkowski K, Dulal K, Cheng T, Hjortø GM, Larsen O, Burg JS, Jarvis MA, Garcia KC, Zhu H, Kledal TN, Rosenkilde MM. Spiess K, et al. Among authors: rosenkilde mm. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8427-32. doi: 10.1073/pnas.1509392112. Epub 2015 Jun 15. Proc Natl Acad Sci U S A. 2015. PMID: 26080445 Free PMC article.
Probing Biased Signaling in Chemokine Receptors.
Amarandi RM, Hjortø GM, Rosenkilde MM, Karlshøj S. Amarandi RM, et al. Among authors: rosenkilde mm. Methods Enzymol. 2016;570:155-86. doi: 10.1016/bs.mie.2015.09.001. Epub 2015 Nov 14. Methods Enzymol. 2016. PMID: 26921946 Review.
Signaling via G proteins mediates tumorigenic effects of GPR87.
Niss Arfelt K, Fares S, Sparre-Ulrich AH, Hjortø GM, Gasbjerg LS, Mølleskov-Jensen AS, Benned-Jensen T, Rosenkilde MM. Niss Arfelt K, et al. Among authors: rosenkilde mm. Cell Signal. 2017 Jan;30:9-18. doi: 10.1016/j.cellsig.2016.11.009. Epub 2016 Nov 16. Cell Signal. 2017. PMID: 27865873
288 results