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Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.
Staus DP, Strachan RT, Manglik A, Pani B, Kahsai AW, Kim TH, Wingler LM, Ahn S, Chatterjee A, Masoudi A, Kruse AC, Pardon E, Steyaert J, Weis WI, Prosser RS, Kobilka BK, Costa T, Lefkowitz RJ. Staus DP, et al. Among authors: lefkowitz rj. Nature. 2016 Jul 21;535(7612):448-52. doi: 10.1038/nature18636. Epub 2016 Jul 13. Nature. 2016. PMID: 27409812 Free PMC article.
The new biology of drug receptors.
Lefkowitz RJ, Kobilka BK, Caron MG. Lefkowitz RJ, et al. Biochem Pharmacol. 1989 Sep 15;38(18):2941-8. doi: 10.1016/0006-2952(89)90001-4. Biochem Pharmacol. 1989. PMID: 2551299 Review. No abstract available.
815 results