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Expression of p53 synergistically augments caspases-mediated apoptosis induced by replication-competent adenoviruses in pancreatic carcinoma cells.
Takei Y, Okamoto S, Kawamura K, Jiang Y, Morinaga T, Shingyoji M, Sekine I, Kubo S, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Yamaguchi N, Tagawa M. Takei Y, et al. Among authors: morinaga t. Cancer Gene Ther. 2015 Sep;22(9):445-53. doi: 10.1038/cgt.2015.33. Epub 2015 Aug 7. Cancer Gene Ther. 2015. PMID: 26251031
Replication-competent adenoviruses with the type 35-derived fiber-knob region achieve reactive oxygen species-dependent cytotoxicity and produce greater toxicity than those with the type 5-derived region in pancreatic carcinoma.
Yamauchi S, Kawamura K, Okamoto S, Morinaga T, Jiang Y, Shingyoji M, Sekine I, Kubo S, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M. Yamauchi S, et al. Among authors: morinaga t. Apoptosis. 2015 Dec;20(12):1587-98. doi: 10.1007/s10495-015-1171-8. Apoptosis. 2015. PMID: 26373551
Heat shock protein 90 inhibitors augment endogenous wild-type p53 expression but down-regulate the adenovirally-induced expression by inhibiting a proteasome activity.
Chai K, Ning X, Nguyễn TTT, Zhong B, Morinaga T, Li Z, Shingyoji M, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Yamaguchi N, Tagawa M. Chai K, et al. Among authors: morinaga t. Oncotarget. 2018 May 25;9(40):26130-26143. doi: 10.18632/oncotarget.25452. eCollection 2018 May 25. Oncotarget. 2018. PMID: 29899847 Free PMC article.
304 results