Walker D - Search Results

1

Structural and biophysical analysis of nuclease protein antibiotics.

Klein A, Wojdyla JA, Joshi A, Josts I, McCaughey LC, Housden NG, Kaminska R, Byron O, Walker D, Kleanthous C. Klein A, et al. Among authors: walker d. Biochem J. 2016 Sep 15;473(18):2799-812. doi: 10.1042/BCJ20160544. Epub 2016 Jul 8. Biochem J. 2016. PMID: 27402794 Free PMC article.

2

Inhibition of a ribosome-inactivating ribonuclease: the crystal structure of the cytotoxic domain of colicin E3 in complex with its immunity protein.

Carr S, Walker D, James R, Kleanthous C, Hemmings AM. Carr S, et al. Among authors: walker d. Structure. 2000 Sep 15;8(9):949-60. doi: 10.1016/s0969-2126(00)00186-6. Structure. 2000. PMID: 10986462 Free article.

3

Crystallization of the cytotoxic domain of a ribosome-inactivating colicin in complex with its immunity protein.

Carr S, Walker D, James R, Kleanthous C, Hemmings AM. Carr S, et al. Among authors: walker d. Acta Crystallogr D Biol Crystallogr. 2000 Dec;56(Pt 12):1630-3. doi: 10.1107/s0907444900010726. Acta Crystallogr D Biol Crystallogr. 2000. PMID: 11092930

4

Immunity proteins: enzyme inhibitors that avoid the active site.

Kleanthous C, Walker D. Kleanthous C, et al. Among authors: walker d. Trends Biochem Sci. 2001 Oct;26(10):624-31. doi: 10.1016/s0968-0004(01)01941-7. Trends Biochem Sci. 2001. PMID: 11590016 Review.

5

Mechanism and cleavage specificity of the H-N-H endonuclease colicin E9.

Pommer AJ, Cal S, Keeble AH, Walker D, Evans SJ, Kühlmann UC, Cooper A, Connolly BA, Hemmings AM, Moore GR, James R, Kleanthous C. Pommer AJ, et al. Among authors: walker d. J Mol Biol. 2001 Dec 7;314(4):735-49. doi: 10.1006/jmbi.2001.5189. J Mol Biol. 2001. PMID: 11733993

6

Mutagenic scan of the H-N-H motif of colicin E9: implications for the mechanistic enzymology of colicins, homing enzymes and apoptotic endonucleases.

Walker DC, Georgiou T, Pommer AJ, Walker D, Moore GR, Kleanthous C, James R. Walker DC, et al. Among authors: walker d. Nucleic Acids Res. 2002 Jul 15;30(14):3225-34. doi: 10.1093/nar/gkf420. Nucleic Acids Res. 2002. PMID: 12136104 Free PMC article.

7

Thermodynamic consequences of bipartite immunity protein binding to the ribosomal ribonuclease colicin E3.

Walker D, Moore GR, James R, Kleanthous C. Walker D, et al. Biochemistry. 2003 Apr 15;42(14):4161-71. doi: 10.1021/bi0273720. Biochemistry. 2003. PMID: 12680770

8

OmpF enhances the ability of BtuB to protect susceptible Escherichia coli cells from colicin E9 cytotoxicity.

Law CJ, Penfold CN, Walker DC, Moore GR, James R, Kleanthous C. Law CJ, et al. FEBS Lett. 2003 Jun 19;545(2-3):127-32. doi: 10.1016/s0014-5793(03)00511-8. FEBS Lett. 2003. PMID: 12804762 Free article.

9

Transcriptional profiling of colicin-induced cell death of Escherichia coli MG1655 identifies potential mechanisms by which bacteriocins promote bacterial diversity.

Walker D, Rolfe M, Thompson A, Moore GR, James R, Hinton JC, Kleanthous C. Walker D, et al. J Bacteriol. 2004 Feb;186(3):866-9. doi: 10.1128/JB.186.3.866-869.2004. J Bacteriol. 2004. PMID: 14729715 Free PMC article.

10

Destabilization of the colicin E9 Endonuclease domain by interaction with negatively charged phospholipids: implications for colicin translocation into bacteria.

Mosbahi K, Walker D, Lea E, Moore GR, James R, Kleanthous C. Mosbahi K, et al. Among authors: walker d. J Biol Chem. 2004 May 21;279(21):22145-51. doi: 10.1074/jbc.M400402200. Epub 2004 Mar 23. J Biol Chem. 2004. PMID: 15044477 Free article.

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