Paveley R - Search Results

1

Discovery of New Anti-Schistosomal Hits by Integration of QSAR-Based Virtual Screening and High Content Screening.

Neves BJ, Dantas RF, Senger MR, Melo-Filho CC, Valente WC, de Almeida AC, Rezende-Neto JM, Lima EF, Paveley R, Furnham N, Muratov E, Kamentsky L, Carpenter AE, Braga RC, Silva-Junior FP, Andrade CH. Neves BJ, et al. Among authors: paveley r. J Med Chem. 2016 Aug 11;59(15):7075-88. doi: 10.1021/acs.jmedchem.5b02038. Epub 2016 Jul 22. J Med Chem. 2016. PMID: 27396732 Free PMC article.

2

QSAR-Driven Discovery of Novel Chemical Scaffolds Active against Schistosoma mansoni.

Melo-Filho CC, Dantas RF, Braga RC, Neves BJ, Senger MR, Valente WC, Rezende-Neto JM, Chaves WT, Muratov EN, Paveley RA, Furnham N, Kamentsky L, Carpenter AE, Silva-Junior FP, Andrade CH. Melo-Filho CC, et al. Among authors: paveley ra. J Chem Inf Model. 2016 Jul 25;56(7):1357-72. doi: 10.1021/acs.jcim.6b00055. Epub 2016 Jun 16. J Chem Inf Model. 2016. PMID: 27253773 Free PMC article.

3

Computationally-guided drug repurposing enables the discovery of kinase targets and inhibitors as new schistosomicidal agents.

Giuliani S, Silva AC, Borba JVVB, Ramos PIP, Paveley RA, Muratov EN, Andrade CH, Furnham N. Giuliani S, et al. Among authors: paveley ra. PLoS Comput Biol. 2018 Oct 22;14(10):e1006515. doi: 10.1371/journal.pcbi.1006515. eCollection 2018 Oct. PLoS Comput Biol. 2018. PMID: 30346968 Free PMC article.

4

Whole organism high-content screening by label-free, image-based Bayesian classification for parasitic diseases.

Paveley RA, Mansour NR, Hallyburton I, Bleicher LS, Benn AE, Mikic I, Guidi A, Gilbert IH, Hopkins AL, Bickle QD. Paveley RA, et al. PLoS Negl Trop Dis. 2012;6(7):e1762. doi: 10.1371/journal.pntd.0001762. Epub 2012 Jul 31. PLoS Negl Trop Dis. 2012. PMID: 22860151 Free PMC article.

5

High Throughput Screening Identifies Novel Lead Compounds with Activity against Larval, Juvenile and Adult Schistosoma mansoni.

Mansour NR, Paveley R, Gardner JM, Bell AS, Parkinson T, Bickle Q. Mansour NR, et al. Among authors: paveley r. PLoS Negl Trop Dis. 2016 Apr 29;10(4):e0004659. doi: 10.1371/journal.pntd.0004659. eCollection 2016 Apr. PLoS Negl Trop Dis. 2016. PMID: 27128493 Free PMC article.

6

Automated imaging and other developments in whole-organism anthelmintic screening.

Paveley RA, Bickle QD. Paveley RA, et al. Parasite Immunol. 2013 Sep-Oct;35(9-10):302-13. doi: 10.1111/pim.12037. Parasite Immunol. 2013. PMID: 23581722 Review.

7

Application of RNAi to Genomic Drug Target Validation in Schistosomes.

Guidi A, Mansour NR, Paveley RA, Carruthers IM, Besnard J, Hopkins AL, Gilbert IH, Bickle QD. Guidi A, et al. Among authors: paveley ra. PLoS Negl Trop Dis. 2015 May 20;9(5):e0003801. doi: 10.1371/journal.pntd.0003801. eCollection 2015 May. PLoS Negl Trop Dis. 2015. PMID: 25992548 Free PMC article.

8

Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells.

Paveley RA, Aynsley SA, Cook PC, Turner JD, Mountford AP. Paveley RA, et al. PLoS Negl Trop Dis. 2009 Oct 13;3(10):e528. doi: 10.1371/journal.pntd.0000528. PLoS Negl Trop Dis. 2009. PMID: 19829705 Free PMC article.

9

CD4+CD25+ regulatory cells contribute to the regulation of colonic Th2 granulomatous pathology caused by schistosome infection.

Turner JD, Jenkins GR, Hogg KG, Aynsley SA, Paveley RA, Cook PC, Coles MC, Mountford AP. Turner JD, et al. Among authors: paveley ra. PLoS Negl Trop Dis. 2011 Aug;5(8):e1269. doi: 10.1371/journal.pntd.0001269. Epub 2011 Aug 9. PLoS Negl Trop Dis. 2011. PMID: 21858239 Free PMC article.

10

CD207+ Langerhans cells constitute a minor population of skin-derived antigen-presenting cells in the draining lymph node following exposure to Schistosoma mansoni.

Kumkate S, Jenkins GR, Paveley RA, Hogg KG, Mountford AP. Kumkate S, et al. Among authors: paveley ra. Int J Parasitol. 2007 Feb;37(2):209-20. doi: 10.1016/j.ijpara.2006.10.007. Epub 2006 Nov 27. Int J Parasitol. 2007. PMID: 17157855 Free PMC article.

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