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SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair.
Hewitt G, Carroll B, Sarallah R, Correia-Melo C, Ogrodnik M, Nelson G, Otten EG, Manni D, Antrobus R, Morgan BA, von Zglinicki T, Jurk D, Seluanov A, Gorbunova V, Johansen T, Passos JF, Korolchuk VI. Hewitt G, et al. Among authors: nelson g. Autophagy. 2016 Oct 2;12(10):1917-1930. doi: 10.1080/15548627.2016.1210368. Epub 2016 Jul 8. Autophagy. 2016. PMID: 27391408 Free PMC article.
ssDNA fragments induce cell senescence by telomere uncapping.
Tsolou A, Passos JF, Nelson G, Arai Y, Zglinicki Tv. Tsolou A, et al. Among authors: nelson g. Exp Gerontol. 2008 Oct;43(10):892-9. doi: 10.1016/j.exger.2008.08.043. Epub 2008 Aug 22. Exp Gerontol. 2008. PMID: 18778766
DNA damage response and cellular senescence in tissues of aging mice.
Wang C, Jurk D, Maddick M, Nelson G, Martin-Ruiz C, von Zglinicki T. Wang C, et al. Among authors: nelson g. Aging Cell. 2009 Jun;8(3):311-23. doi: 10.1111/j.1474-9726.2009.00481.x. Epub 2009 Apr 9. Aging Cell. 2009. PMID: 19627270 Free article.
DNA damage foci in mitosis are devoid of 53BP1.
Nelson G, Buhmann M, von Zglinicki T. Nelson G, et al. Cell Cycle. 2009 Oct 15;8(20):3379-83. doi: 10.4161/cc.8.20.9857. Epub 2009 Oct 19. Cell Cycle. 2009. PMID: 19806024
Shifting focus.
Nelson G, von Zglinicki T. Nelson G, et al. Cell Cycle. 2010 Feb 1;9(3):443-4. Epub 2010 Feb 1. Cell Cycle. 2010. PMID: 20130449 No abstract available.
Feedback between p21 and reactive oxygen production is necessary for cell senescence.
Passos JF, Nelson G, Wang C, Richter T, Simillion C, Proctor CJ, Miwa S, Olijslagers S, Hallinan J, Wipat A, Saretzki G, Rudolph KL, Kirkwood TB, von Zglinicki T. Passos JF, et al. Among authors: nelson g. Mol Syst Biol. 2010;6:347. doi: 10.1038/msb.2010.5. Epub 2010 Feb 16. Mol Syst Biol. 2010. PMID: 20160708 Free PMC article.
A senescent cell bystander effect: senescence-induced senescence.
Nelson G, Wordsworth J, Wang C, Jurk D, Lawless C, Martin-Ruiz C, von Zglinicki T. Nelson G, et al. Aging Cell. 2012 Apr;11(2):345-9. doi: 10.1111/j.1474-9726.2012.00795.x. Epub 2012 Feb 9. Aging Cell. 2012. PMID: 22321662 Free PMC article.
1,907 results