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Page 1
A population pharmacokinetic model for perioperative dosing of factor VIII in hemophilia A patients.
Hazendonk H, Fijnvandraat K, Lock J, Driessens M, van der Meer F, Meijer K, Kruip M, Gorkom BL, Peters M, de Wildt S, Leebeek F, Cnossen M, Mathôt R; “OPTI-CLOT” study group. Hazendonk H, et al. Among authors: driessens m. Haematologica. 2016 Oct;101(10):1159-1169. doi: 10.3324/haematol.2015.136275. Epub 2016 Jul 6. Haematologica. 2016. PMID: 27390359 Free PMC article.
The "OPTI-CLOT" trial. A randomised controlled trial on periOperative PharmacokineTIc-guided dosing of CLOTting factor concentrate in haemophilia A.
Hazendonk HC, van Moort I, Fijnvandraat K, Kruip MJ, Laros-van Gorkom BA, van der Meer FJ, Meijer K, Peters M, Schutgens RE, Zwaan CM, Driessens MH, Polinder S, Leebeek FW, Mathôt RA, Cnossen MH. Hazendonk HC, et al. Among authors: driessens mh. Thromb Haemost. 2015 Aug 31;114(3):639-44. doi: 10.1160/TH14-11-0925. Epub 2015 Jun 11. Thromb Haemost. 2015. PMID: 26062822 Clinical Trial.
Desmopressin treatment combined with clotting factor VIII concentrates in patients with non-severe haemophilia A: protocol for a multicentre single-armed trial, the DAVID study.
Schütte LM, Cnossen MH, van Hest RM, Driessens MHE, Fijnvandraat K, Polinder S, Beckers EAM, Coppens M, Eikenboom J, Laros-van Gorkom BAP, Meijer K, Nieuwenhuizen L, Mauser-Bunschoten EP, Leebeek FWG, Mathôt RAA, Kruip MJHA. Schütte LM, et al. Among authors: driessens mhe. BMJ Open. 2019 Apr 23;9(4):e022719. doi: 10.1136/bmjopen-2018-022719. BMJ Open. 2019. PMID: 31015264 Free PMC article.
Patient Perspectives on Novel Treatments in Haemophilia: A Qualitative Study.
van Balen EC, Wesselo ML, Baker BL, Westerman MJ, Coppens M, Smit C, Driessens MHE, Leebeek FWG, van der Bom JG, Gouw SC. van Balen EC, et al. Among authors: driessens mhe. Patient. 2020 Apr;13(2):201-210. doi: 10.1007/s40271-019-00395-6. Patient. 2020. PMID: 31691206 Free PMC article.
Mortality, life expectancy, and causes of death of persons with hemophilia in the Netherlands 2001-2018.
Hassan S, Monahan RC, Mauser-Bunschoten EP, van Vulpen LFD, Eikenboom J, Beckers EAM, Hooimeijer L, Ypma PF, Nieuwenhuizen L, Coppens M, Schols SEM, Leebeek FWG, Smit C, Driessens MH, le Cessie S, van Balen EC, Rosendaal FR, van der Bom JG, Gouw SC. Hassan S, et al. Among authors: driessens mh. J Thromb Haemost. 2021 Mar;19(3):645-653. doi: 10.1111/jth.15182. Epub 2020 Dec 18. J Thromb Haemost. 2021. PMID: 33217158 Free PMC article.
Validation of a perioperative population factor VIII pharmacokinetic model with a large cohort of pediatric hemophilia a patients.
Preijers T, Liesner R, Hazendonk HCAM, Chowdary P, Driessens MHE, Hart DP, Laros-van Gorkom BAP, van der Meer FJM, Meijer K, Fijnvandraat K, Leebeek FWG, Mathôt RAA, Cnossen MH; “OPTI-CLOT” study group. Preijers T, et al. Among authors: driessens mhe. Br J Clin Pharmacol. 2021 Nov;87(11):4408-4420. doi: 10.1111/bcp.14864. Epub 2021 May 4. Br J Clin Pharmacol. 2021. PMID: 33884664 Free PMC article.
Health and treatment outcomes of patients with hemophilia in the Netherlands, 1972-2019.
Hassan S, van Balen EC, Smit C, Mauser-Bunschoten EP, van Vulpen LFD, Eikenboom J, Beckers EAM, Hooimeijer L, Ypma PF, Nieuwenhuizen L, Coppens M, Schols SEM, Leebeek FWG, Driessens MH, Rosendaal FR, van der Bom JG, Gouw SC. Hassan S, et al. Among authors: driessens mh. J Thromb Haemost. 2021 Oct;19(10):2394-2406. doi: 10.1111/jth.15424. Epub 2021 Jul 7. J Thromb Haemost. 2021. PMID: 34117710 Free PMC article.
Similar sports participation as the general population in Dutch persons with haemophilia; results from a nationwide study.
Versloot O, van Balen EC, Hassan S, Schols SEM, Leebeek FWG, Eikenboom J, Coppens M, van Vulpen LFD, Smit C, Driessens MHE, van der Net J, Gouw SC, Fischer K; Haemophilia in the Netherlands 6 steering committee. Versloot O, et al. Among authors: driessens mhe. Haemophilia. 2021 Sep;27(5):876-885. doi: 10.1111/hae.14366. Epub 2021 Jun 19. Haemophilia. 2021. PMID: 34146370 Free PMC article.
Perioperative pharmacokinetic-guided factor VIII concentrate dosing in haemophilia (OPTI-CLOT trial): an open-label, multicentre, randomised, controlled trial.
van Moort I, Preijers T, Bukkems LH, Hazendonk HCAM, van der Bom JG, Laros-van Gorkom BAP, Beckers EAM, Nieuwenhuizen L, van der Meer FJM, Ypma P, Coppens M, Fijnvandraat K, Schutgens REG, Meijer K, Leebeek FWG, Mathôt RAA, Cnossen MH; OPTI-CLOT study group. van Moort I, et al. Lancet Haematol. 2021 Jul;8(7):e492-e502. doi: 10.1016/S2352-3026(21)00135-6. Lancet Haematol. 2021. PMID: 34171280 Clinical Trial.
Validation of PROMIS Profile-29 in adults with hemophilia in the Netherlands.
van Balen EC, Haverman L, Hassan S, Taal EM, Smit C, Driessens MH, Beckers EAM, Coppens M, Eikenboom J, Hooimeijer HL, Leebeek FWG, van Vulpen LFD, Schols SEM, Terwee CB, Rosendaal FR, van der Bom JG, Gouw SC. van Balen EC, et al. Among authors: driessens mh. J Thromb Haemost. 2021 Nov;19(11):2687-2701. doi: 10.1111/jth.15454. Epub 2021 Aug 3. J Thromb Haemost. 2021. PMID: 34245088 Free PMC article.
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