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Technical validation of an RT-qPCR in vitro diagnostic test system for the determination of breast cancer molecular subtypes by quantification of ERBB2, ESR1, PGR and MKI67 mRNA levels from formalin-fixed paraffin-embedded breast tumor specimens.
Laible M, Schlombs K, Kaiser K, Veltrup E, Herlein S, Lakis S, Stöhr R, Eidt S, Hartmann A, Wirtz RM, Sahin U. Laible M, et al. Among authors: sahin u. BMC Cancer. 2016 Jul 7;16:398. doi: 10.1186/s12885-016-2476-x. BMC Cancer. 2016. PMID: 27389414 Free PMC article.
Biological subtyping of early breast cancer: a study comparing RT-qPCR with immunohistochemistry.
Wirtz RM, Sihto H, Isola J, Heikkilä P, Kellokumpu-Lehtinen PL, Auvinen P, Turpeenniemi-Hujanen T, Jyrkkiö S, Lakis S, Schlombs K, Laible M, Weber S, Eidt S, Sahin U, Joensuu H. Wirtz RM, et al. Among authors: sahin u. Breast Cancer Res Treat. 2016 Jun;157(3):437-46. doi: 10.1007/s10549-016-3835-7. Epub 2016 May 24. Breast Cancer Res Treat. 2016. PMID: 27220750 Free PMC article.
An international reproducibility study validating quantitative determination of ERBB2, ESR1, PGR, and MKI67 mRNA in breast cancer using MammaTyper®.
Varga Z, Lebeau A, Bu H, Hartmann A, Penault-Llorca F, Guerini-Rocco E, Schraml P, Symmans F, Stoehr R, Teng X, Turzynski A, von Wasielewski R, Gürtler C, Laible M, Schlombs K, Joensuu H, Keller T, Sinn P, Sahin U, Bartlett J, Viale G. Varga Z, et al. Among authors: sahin u. Breast Cancer Res. 2017 May 11;19(1):55. doi: 10.1186/s13058-017-0848-z. Breast Cancer Res. 2017. PMID: 28490348 Free PMC article. Clinical Trial.
Prognostic impact of CD4-positive T cell subsets in early breast cancer: a study based on the FinHer trial patient population.
Schmidt M, Weyer-Elberich V, Hengstler JG, Heimes AS, Almstedt K, Gerhold-Ay A, Lebrecht A, Battista MJ, Hasenburg A, Sahin U, Kalogeras KT, Kellokumpu-Lehtinen PL, Fountzilas G, Wirtz RM, Joensuu H. Schmidt M, et al. Among authors: sahin u. Breast Cancer Res. 2018 Feb 26;20(1):15. doi: 10.1186/s13058-018-0942-x. Breast Cancer Res. 2018. PMID: 29482642 Free PMC article. Clinical Trial.
Impact of molecular subtypes on the prediction of distant recurrence in estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2) negative breast cancer upon five years of endocrine therapy.
Laible M, Hartmann K, Gürtler C, Anzeneder T, Wirtz R, Weber S, Keller T, Sahin U, Rees M, Ramaswamy A. Laible M, et al. Among authors: sahin u. BMC Cancer. 2019 Jul 15;19(1):694. doi: 10.1186/s12885-019-5890-z. BMC Cancer. 2019. PMID: 31307414 Free PMC article.
The tight junction protein claudin 6 is a potential target for patient-individualized treatment in esophageal and gastric adenocarcinoma and is associated with poor prognosis.
Simon AG, Lyu SI, Laible M, Wöll S, Türeci Ö, Şahin U, Alakus H, Fahrig L, Zander T, Buettner R, Bruns CJ, Schroeder W, Gebauer F, Quaas A. Simon AG, et al. Among authors: sahin u. J Transl Med. 2023 Aug 17;21(1):552. doi: 10.1186/s12967-023-04433-8. J Transl Med. 2023. PMID: 37592303 Free PMC article.
503 results