Bolognini D - Search Results

1

A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi-functional Bias.

Bolognini D, Moss CE, Nilsson K, Petersson AU, Donnelly I, Sergeev E, König GM, Kostenis E, Kurowska-Stolarska M, Miller A, Dekker N, Tobin AB, Milligan G. Bolognini D, et al. J Biol Chem. 2016 Sep 2;291(36):18915-31. doi: 10.1074/jbc.M116.736157. Epub 2016 Jul 5. J Biol Chem. 2016. PMID: 27385588 Free PMC article.

2

The Pharmacology and Function of Receptors for Short-Chain Fatty Acids.

Bolognini D, Tobin AB, Milligan G, Moss CE. Bolognini D, et al. Mol Pharmacol. 2016 Mar;89(3):388-98. doi: 10.1124/mol.115.102301. Epub 2015 Dec 30. Mol Pharmacol. 2016. PMID: 26719580 Free article. Review.

3

Ligands at the Free Fatty Acid Receptors 2/3 (GPR43/GPR41).

Milligan G, Bolognini D, Sergeev E. Milligan G, et al. Among authors: bolognini d. Handb Exp Pharmacol. 2017;236:17-32. doi: 10.1007/164_2016_49. Handb Exp Pharmacol. 2017. PMID: 27757758 Review.

4

A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias.

Sergeev E, Hansen AH, Bolognini D, Kawakami K, Kishi T, Aoki J, Ulven T, Inoue A, Hudson BD, Milligan G. Sergeev E, et al. Among authors: bolognini d. Sci Rep. 2017 Oct 23;7(1):13741. doi: 10.1038/s41598-017-14096-3. Sci Rep. 2017. PMID: 29061999 Free PMC article.

5

Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties.

Hansen AH, Sergeev E, Bolognini D, Sprenger RR, Ekberg JH, Ejsing CS, McKenzie CJ, Rexen Ulven E, Milligan G, Ulven T. Hansen AH, et al. Among authors: bolognini d. J Med Chem. 2018 Nov 8;61(21):9534-9550. doi: 10.1021/acs.jmedchem.8b00855. Epub 2018 Oct 12. J Med Chem. 2018. PMID: 30247908 Free article.

6

Chemogenetics defines receptor-mediated functions of short chain free fatty acids.

Bolognini D, Barki N, Butcher AJ, Hudson BD, Sergeev E, Molloy C, Moss CE, Bradley SJ, Le Gouill C, Bouvier M, Tobin AB, Milligan G. Bolognini D, et al. Nat Chem Biol. 2019 May;15(5):489-498. doi: 10.1038/s41589-019-0270-1. Epub 2019 Apr 15. Nat Chem Biol. 2019. PMID: 30992568 Free article.

7

On-target and off-target effects of novel orthosteric and allosteric activators of GPR84.

Mancini SJ, Mahmud ZA, Jenkins L, Bolognini D, Newman R, Barnes M, Edye ME, McMahon SB, Tobin AB, Milligan G. Mancini SJ, et al. Among authors: bolognini d. Sci Rep. 2019 Feb 12;9(1):1861. doi: 10.1038/s41598-019-38539-1. Sci Rep. 2019. PMID: 30755705 Free PMC article.

8

Metabolic and inflammatory functions of short-chain fatty acid receptors.

Bolognini D, Dedeo D, Milligan G. Bolognini D, et al. Curr Opin Endocr Metab Res. 2021 Feb;16:1-9. doi: 10.1016/j.coemr.2020.06.005. Epub 2020 Jul 3. Curr Opin Endocr Metab Res. 2021. PMID: 32835130 Free PMC article. Review.

9

Chemogenetics defines a short-chain fatty acid receptor gut-brain axis.

Barki N, Bolognini D, Börjesson U, Jenkins L, Riddell J, Hughes DI, Ulven T, Hudson BD, Ulven ER, Dekker N, Tobin AB, Milligan G. Barki N, et al. Among authors: bolognini d. Elife. 2022 Mar 1;11:e73777. doi: 10.7554/eLife.73777. Elife. 2022. PMID: 35229717 Free PMC article.

10

CB(1) receptor allosteric modulators display both agonist and signaling pathway specificity.

Baillie GL, Horswill JG, Anavi-Goffer S, Reggio PH, Bolognini D, Abood ME, McAllister S, Strange PG, Stephens GJ, Pertwee RG, Ross RA. Baillie GL, et al. Among authors: bolognini d. Mol Pharmacol. 2013 Feb;83(2):322-38. doi: 10.1124/mol.112.080879. Epub 2012 Nov 15. Mol Pharmacol. 2013. PMID: 23160940 Free PMC article.

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