Episodic β-cell death and dedifferentiation during diet-induced obesity and dysglycemia in male mice.
Tersey SA, Levasseur EM, Syed F, Farb TB, Orr KS, Nelson JB, Shaw JL, Bokvist K, Mather KJ, Mirmira RG.
Tersey SA, et al. Among authors: syed f.
FASEB J. 2018 May 29;32(11):fj201800150RR. doi: 10.1096/fj.201800150RR. Online ahead of print.
FASEB J. 2018.
PMID: 29812970
Free PMC article.
In conclusion, early episodic beta-cell death may be a feature of cellular turnover correlated with changes in glycemia during beta-cell mass accrual in obesity, whereas beta-cell dedifferentiation may be a feature seen later in established disease.-Tersey, S. A., Levasseur, E. M …
In conclusion, early episodic beta-cell death may be a feature of cellular turnover correlated with changes in glycemia during beta-cell mas …