Huang WY - Search Results

1

Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS.

Huang WY, Yan Q, Lin WC, Chung JK, Hansen SD, Christensen SM, Tu HL, Kuriyan J, Groves JT. Huang WY, et al. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8218-23. doi: 10.1073/pnas.1602602113. Epub 2016 Jul 1. Proc Natl Acad Sci U S A. 2016. PMID: 27370798 Free PMC article.

2

H-Ras forms dimers on membrane surfaces via a protein-protein interface.

Lin WC, Iversen L, Tu HL, Rhodes C, Christensen SM, Iwig JS, Hansen SD, Huang WY, Groves JT. Lin WC, et al. Among authors: huang wy. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):2996-3001. doi: 10.1073/pnas.1321155111. Epub 2014 Feb 10. Proc Natl Acad Sci U S A. 2014. PMID: 24516166 Free PMC article.

3

Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner.

Lowe AR, Tang JH, Yassif J, Graf M, Huang WY, Groves JT, Weis K, Liphardt JT. Lowe AR, et al. Among authors: huang wy. Elife. 2015 Mar 6;4:e04052. doi: 10.7554/eLife.04052. Elife. 2015. PMID: 25748139 Free PMC article.

4

E-cadherin junction formation involves an active kinetic nucleation process.

Biswas KH, Hartman KL, Yu CH, Harrison OJ, Song H, Smith AW, Huang WY, Lin WC, Guo Z, Padmanabhan A, Troyanovsky SM, Dustin ML, Shapiro L, Honig B, Zaidel-Bar R, Groves JT. Biswas KH, et al. Among authors: huang wy. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):10932-7. doi: 10.1073/pnas.1513775112. Epub 2015 Aug 19. Proc Natl Acad Sci U S A. 2015. PMID: 26290581 Free PMC article.

5

Two-step membrane binding by the bacterial SRP receptor enable efficient and accurate Co-translational protein targeting.

Hwang Fu YH, Huang WYC, Shen K, Groves JT, Miller T, Shan SO. Hwang Fu YH, et al. Elife. 2017 Jul 28;6:e25885. doi: 10.7554/eLife.25885. Elife. 2017. PMID: 28753124 Free PMC article.

6

Dynamic Scaling Analysis of Molecular Motion within the LAT:Grb2:SOS Protein Network on Membranes.

Huang WYC, Chiang HK, Groves JT. Huang WYC, et al. Biophys J. 2017 Oct 17;113(8):1807-1813. doi: 10.1016/j.bpj.2017.08.024. Biophys J. 2017. PMID: 29045874 Free PMC article.

7

Allosteric Modulation of Grb2 Recruitment to the Intrinsically Disordered Scaffold Protein, LAT, by Remote Site Phosphorylation.

Huang WYC, Ditlev JA, Chiang HK, Rosen MK, Groves JT. Huang WYC, et al. J Am Chem Soc. 2017 Dec 13;139(49):18009-18015. doi: 10.1021/jacs.7b09387. Epub 2017 Nov 28. J Am Chem Soc. 2017. PMID: 29182244 Free PMC article.

8

A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS.

Huang WYC, Alvarez S, Kondo Y, Lee YK, Chung JK, Lam HYM, Biswas KH, Kuriyan J, Groves JT. Huang WYC, et al. Science. 2019 Mar 8;363(6431):1098-1103. doi: 10.1126/science.aau5721. Epub 2019 Mar 7. Science. 2019. PMID: 30846600 Free PMC article.

9

Stochastic geometry sensing and polarization in a lipid kinase-phosphatase competitive reaction.

Hansen SD, Huang WYC, Lee YK, Bieling P, Christensen SM, Groves JT. Hansen SD, et al. Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):15013-15022. doi: 10.1073/pnas.1901744116. Epub 2019 Jul 5. Proc Natl Acad Sci U S A. 2019. PMID: 31278151 Free PMC article.

10

Coupled membrane lipid miscibility and phosphotyrosine-driven protein condensation phase transitions.

Chung JK, Huang WYC, Carbone CB, Nocka LM, Parikh AN, Vale RD, Groves JT. Chung JK, et al. Biophys J. 2021 Apr 6;120(7):1257-1265. doi: 10.1016/j.bpj.2020.09.017. Epub 2020 Sep 24. Biophys J. 2021. PMID: 33080222 Free PMC article.

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