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Quantitative preclinical imaging of TSPO expression in glioma using N,N-diethyl-2-(2-(4-(2-18F-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide.
Tang D, Hight MR, McKinley ET, Fu A, Buck JR, Smith RA, Tantawy MN, Peterson TE, Colvin DC, Ansari MS, Nickels M, Manning HC. Tang D, et al. Among authors: manning hc. J Nucl Med. 2012 Feb;53(2):287-94. doi: 10.2967/jnumed.111.095653. Epub 2012 Jan 17. J Nucl Med. 2012. PMID: 22251555 Free PMC article.
Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[(18)F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer.
Cheung YY, Nickels ML, Tang D, Buck JR, Manning HC. Cheung YY, et al. Among authors: manning hc. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4466-4471. doi: 10.1016/j.bmcl.2014.07.091. Epub 2014 Aug 8. Bioorg Med Chem Lett. 2014. PMID: 25172419 Free PMC article.
109 results