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Inhibition of PI3K promotes dilation of human small airways in a rho kinase-dependent manner.
Koziol-White CJ, Yoo EJ, Cao G, Zhang J, Papanikolaou E, Pushkarsky I, Andrews A, Himes BE, Damoiseaux RD, Liggett SB, Di Carlo D, Kurten RC, Panettieri RA Jr. Koziol-White CJ, et al. Among authors: himes be. Br J Pharmacol. 2016 Sep;173(18):2726-38. doi: 10.1111/bph.13542. Epub 2016 Aug 3. Br J Pharmacol. 2016. PMID: 27352269 Free PMC article.
RNA-Seq transcriptome profiling identifies CRISPLD2 as a glucocorticoid responsive gene that modulates cytokine function in airway smooth muscle cells.
Himes BE, Jiang X, Wagner P, Hu R, Wang Q, Klanderman B, Whitaker RM, Duan Q, Lasky-Su J, Nikolos C, Jester W, Johnson M, Panettieri RA Jr, Tantisira KG, Weiss ST, Lu Q. Himes BE, et al. PLoS One. 2014 Jun 13;9(6):e99625. doi: 10.1371/journal.pone.0099625. eCollection 2014. PLoS One. 2014. PMID: 24926665 Free PMC article.
Inhibition of spleen tyrosine kinase attenuates IgE-mediated airway contraction and mediator release in human precision cut lung slices.
Koziol-White CJ, Jia Y, Baltus GA, Cooper PR, Zaller DM, Crackower MA, Sirkowski EE, Smock S, Northrup AB, Himes BE, Alves SE, Panettieri RA Jr. Koziol-White CJ, et al. Among authors: himes be. Br J Pharmacol. 2016 Nov;173(21):3080-3087. doi: 10.1111/bph.13550. Epub 2016 Oct 5. Br J Pharmacol. 2016. PMID: 27417329 Free PMC article.
PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β2-Adrenergic Receptors and Adenylyl Cyclase 6.
Johnstone TB, Smith KH, Koziol-White CJ, Li F, Kazarian AG, Corpuz ML, Shumyatcher M, Ehlert FJ, Himes BE, Panettieri RA Jr, Ostrom RS. Johnstone TB, et al. Among authors: himes be. Am J Respir Cell Mol Biol. 2018 Apr;58(4):530-541. doi: 10.1165/rcmb.2017-0294OC. Am J Respir Cell Mol Biol. 2018. PMID: 29262264 Free PMC article.
129 results