Erasmus E - Search Results

1

Xenobiotic/medium chain fatty acid: CoA ligase - a critical review on its role in fatty acid metabolism and the detoxification of benzoic acid and aspirin.

van der Sluis R, Erasmus E. van der Sluis R, et al. Among authors: erasmus e. Expert Opin Drug Metab Toxicol. 2016 Oct;12(10):1169-79. doi: 10.1080/17425255.2016.1206888. Epub 2016 Jul 15. Expert Opin Drug Metab Toxicol. 2016. PMID: 27351777 Review.

2

Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation.

Badenhorst CP, van der Sluis R, Erasmus E, van Dijk AA. Badenhorst CP, et al. Among authors: erasmus e. Expert Opin Drug Metab Toxicol. 2013 Sep;9(9):1139-53. doi: 10.1517/17425255.2013.796929. Epub 2013 May 8. Expert Opin Drug Metab Toxicol. 2013. PMID: 23650932 Review.

3

A new perspective on the importance of glycine conjugation in the metabolism of aromatic acids.

Badenhorst CP, Erasmus E, van der Sluis R, Nortje C, van Dijk AA. Badenhorst CP, et al. Among authors: erasmus e. Drug Metab Rev. 2014 Aug;46(3):343-61. doi: 10.3109/03602532.2014.908903. Epub 2014 Apr 22. Drug Metab Rev. 2014. PMID: 24754494 Review.

4

Conservation of the coding regions of the glycine N-acyltransferase gene further suggests that glycine conjugation is an essential detoxification pathway.

van der Sluis R, Badenhorst CP, Erasmus E, van Dyk E, van der Westhuizen FH, van Dijk AA. van der Sluis R, et al. Among authors: erasmus e. Gene. 2015 Oct 15;571(1):126-34. doi: 10.1016/j.gene.2015.06.081. Epub 2015 Jul 3. Gene. 2015. PMID: 26149650

5

The Use of p-Aminobenzoic Acid as a Probe Substance for the Targeted Profiling of Glycine Conjugation.

Nortje C, van der Sluis R, van Dijk AA, Erasmus E. Nortje C, et al. Among authors: erasmus e. J Biochem Mol Toxicol. 2016 Mar;30(3):136-47. doi: 10.1002/jbt.21772. Epub 2015 Oct 20. J Biochem Mol Toxicol. 2016. PMID: 26484797

6

New insights into the catalytic mechanism of human glycine N-acyltransferase.

van der Sluis R, Ungerer V, Nortje C, A van Dijk A, Erasmus E. van der Sluis R, et al. Among authors: erasmus e. J Biochem Mol Toxicol. 2017 Nov;31(11). doi: 10.1002/jbt.21963. Epub 2017 Jul 31. J Biochem Mol Toxicol. 2017. PMID: 28759163

7

Increased excretion of c4-carnitine species after a therapeutic acetylsalicylic Acid dose: evidence for an inhibitory effect on short-chain Fatty Acid metabolism.

Mels CM, Jansen van Rensburg P, van der Westhuizen FH, Pretorius PJ, Erasmus E. Mels CM, et al. Among authors: erasmus e. ISRN Pharmacol. 2011;2011:851870. doi: 10.5402/2011/851870. Epub 2011 Feb 22. ISRN Pharmacol. 2011. PMID: 22084721 Free PMC article.

8

The utilization of alanine, glutamic acid, and serine as amino acid substrates for glycine N-acyltransferase.

van der Westhuizen FH, Pretorius PJ, Erasmus E. van der Westhuizen FH, et al. Among authors: erasmus e. J Biochem Mol Toxicol. 2000;14(2):102-9. doi: 10.1002/(sici)1099-0461(2000)14:2<102::aid-jbt6>3.0.co;2-h. J Biochem Mol Toxicol. 2000. PMID: 10630424

9

The simultaneous detection and quantification of p-aminobenzoic acid and its phase 2 biotransformation metabolites in human urine using LC-MS/MS.

Nortje C, Jansen van Rensburg P, Cooke C, Erasmus E. Nortje C, et al. Among authors: erasmus e. Bioanalysis. 2015;7(10):1211-24. doi: 10.4155/bio.15.54. Bioanalysis. 2015. PMID: 26045002

10

Biotransformation profiles from a cohort of chronic fatigue women in response to a hepatic detoxification challenge.

Erasmus E, Steffens FE, van Reenen M, Vorster BC, Reinecke CJ. Erasmus E, et al. PLoS One. 2019 May 10;14(5):e0216298. doi: 10.1371/journal.pone.0216298. eCollection 2019. PLoS One. 2019. PMID: 31075116 Free PMC article.

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