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Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients.
Takeda S, Commins C, DeVos SL, Nobuhara CK, Wegmann S, Roe AD, Costantino I, Fan Z, Nicholls SB, Sherman AE, Trisini Lipsanopoulos AT, Scherzer CR, Carlson GA, Pitstick R, Peskind ER, Raskind MA, Li G, Montine TJ, Frosch MP, Hyman BT. Takeda S, et al. Among authors: nobuhara ck. Ann Neurol. 2016 Sep;80(3):355-67. doi: 10.1002/ana.24716. Epub 2016 Aug 3. Ann Neurol. 2016. PMID: 27351289 Free PMC article.
Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.
Nobuhara CK, DeVos SL, Commins C, Wegmann S, Moore BD, Roe AD, Costantino I, Frosch MP, Pitstick R, Carlson GA, Hock C, Nitsch RM, Montrasio F, Grimm J, Cheung AE, Dunah AW, Wittmann M, Bussiere T, Weinreb PH, Hyman BT, Takeda S. Nobuhara CK, et al. Am J Pathol. 2017 Jun;187(6):1399-1412. doi: 10.1016/j.ajpath.2017.01.022. Epub 2017 Apr 11. Am J Pathol. 2017. PMID: 28408124 Free PMC article.
Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain.
DeVos SL, Corjuc BT, Oakley DH, Nobuhara CK, Bannon RN, Chase A, Commins C, Gonzalez JA, Dooley PM, Frosch MP, Hyman BT. DeVos SL, et al. Among authors: nobuhara ck. Front Neurosci. 2018 Apr 24;12:267. doi: 10.3389/fnins.2018.00267. eCollection 2018. Front Neurosci. 2018. PMID: 29740275 Free PMC article.
Postoperative changes in cognition and cerebrospinal fluid neurodegenerative disease biomarkers.
Berger M, Browndyke JN, Cooter Wright M, Nobuhara C, Reese M, Acker L, Bullock WM, Colin BJ, Devinney MJ, Moretti EW, Moul JW, Ohlendorf B, Laskowitz DT, Waligorska T, Shaw LM, Whitson HE, Cohen HJ, Mathew JP; MADCO-PC Investigators. Berger M, et al. Ann Clin Transl Neurol. 2022 Feb;9(2):155-170. doi: 10.1002/acn3.51499. Epub 2022 Feb 1. Ann Clin Transl Neurol. 2022. PMID: 35104057 Free PMC article. Clinical Trial.
Plasma and cerebrospinal fluid inflammation and the blood-brain barrier in older surgical patients: the Role of Inflammation after Surgery for Elders (RISE) study.
Vasunilashorn SM, Ngo LH, Dillon ST, Fong TG, Carlyle BC, Kivisäkk P, Trombetta BA, Vlassakov KV, Kunze LJ, Arnold SE, Xie Z, Inouye SK, Libermann TA, Marcantonio ER; RISE Study Group. Vasunilashorn SM, et al. J Neuroinflammation. 2021 Apr 30;18(1):103. doi: 10.1186/s12974-021-02145-8. J Neuroinflammation. 2021. PMID: 33931093 Free PMC article.
Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development.
Vallabh SM, Nobuhara CK, Llorens F, Zerr I, Parchi P, Capellari S, Kuhn E, Klickstein J, Safar JG, Nery FC, Swoboda KJ, Geschwind MD, Zetterberg H, Arnold SE, Minikel EV, Schreiber SL. Vallabh SM, et al. Among authors: nobuhara ck. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7793-7798. doi: 10.1073/pnas.1901947116. Epub 2019 Apr 1. Proc Natl Acad Sci U S A. 2019. PMID: 30936307 Free PMC article.
Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease.
Vallabh SM, Minikel EV, Williams VJ, Carlyle BC, McManus AJ, Wennick CD, Bolling A, Trombetta BA, Urick D, Nobuhara CK, Gerber J, Duddy H, Lachmann I, Stehmann C, Collins SJ, Blennow K, Zetterberg H, Arnold SE. Vallabh SM, et al. Among authors: nobuhara ck. BMC Med. 2020 Jun 18;18(1):140. doi: 10.1186/s12916-020-01608-8. BMC Med. 2020. PMID: 32552681 Free PMC article.
21 results