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Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration.
Brahmachari S, Ge P, Lee SH, Kim D, Karuppagounder SS, Kumar M, Mao X, Shin JH, Lee Y, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM, Ko HS. Brahmachari S, et al. Among authors: pletnikova o. J Clin Invest. 2016 Aug 1;126(8):2970-88. doi: 10.1172/JCI85456. Epub 2016 Jun 27. J Clin Invest. 2016. PMID: 27348587 Free PMC article.
Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations.
Li W, West N, Colla E, Pletnikova O, Troncoso JC, Marsh L, Dawson TM, Jäkälä P, Hartmann T, Price DL, Lee MK. Li W, et al. Among authors: pletnikova o. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2162-7. doi: 10.1073/pnas.0406976102. Epub 2005 Jan 31. Proc Natl Acad Sci U S A. 2005. PMID: 15684072 Free PMC article.
Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.
Ko HS, von Coelln R, Sriram SR, Kim SW, Chung KK, Pletnikova O, Troncoso J, Johnson B, Saffary R, Goh EL, Song H, Park BJ, Kim MJ, Kim S, Dawson VL, Dawson TM. Ko HS, et al. Among authors: pletnikova o. J Neurosci. 2005 Aug 31;25(35):7968-78. doi: 10.1523/JNEUROSCI.2172-05.2005. J Neurosci. 2005. PMID: 16135753 Free PMC article.
Morphometry of the human substantia nigra in ageing and Parkinson's disease.
Rudow G, O'Brien R, Savonenko AV, Resnick SM, Zonderman AB, Pletnikova O, Marsh L, Dawson TM, Crain BJ, West MJ, Troncoso JC. Rudow G, et al. Among authors: o brien r, pletnikova o. Acta Neuropathol. 2008 Apr;115(4):461-70. doi: 10.1007/s00401-008-0352-8. Epub 2008 Feb 23. Acta Neuropathol. 2008. PMID: 18297291 Free PMC article.
S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease.
Tsang AH, Lee YI, Ko HS, Savitt JM, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM, Chung KK. Tsang AH, et al. Among authors: pletnikova o. Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4900-5. doi: 10.1073/pnas.0810595106. Epub 2009 Mar 9. Proc Natl Acad Sci U S A. 2009. PMID: 19273858 Free PMC article.
131 results