Fitzgerald K - Search Results

1

A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection.

Tzeng TC, Schattgen S, Monks B, Wang D, Cerny A, Latz E, Fitzgerald K, Golenbock DT. Tzeng TC, et al. Among authors: fitzgerald k. Cell Rep. 2016 Jul 12;16(2):571-582. doi: 10.1016/j.celrep.2016.06.011. Epub 2016 Jun 23. Cell Rep. 2016. PMID: 27346360 Free PMC article.

2

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T. Fitzgerald KA, et al. Nat Immunol. 2003 May;4(5):491-6. doi: 10.1038/ni921. Nat Immunol. 2003. PMID: 12692549

3

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.

Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E, Monks B, Pitha PM, Golenbock DT. Fitzgerald KA, et al. J Exp Med. 2003 Oct 6;198(7):1043-55. doi: 10.1084/jem.20031023. Epub 2003 Sep 29. J Exp Med. 2003. PMID: 14517278 Free PMC article.

4

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts.

McWhirter SM, Fitzgerald KA, Rosains J, Rowe DC, Golenbock DT, Maniatis T. McWhirter SM, et al. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):233-8. doi: 10.1073/pnas.2237236100. Epub 2003 Dec 16. Proc Natl Acad Sci U S A. 2004. PMID: 14679297 Free PMC article.

5

TLR9 signals after translocating from the ER to CpG DNA in the lysosome.

Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, Knetter CF, Lien E, Nilsen NJ, Espevik T, Golenbock DT. Latz E, et al. Nat Immunol. 2004 Feb;5(2):190-8. doi: 10.1038/ni1028. Epub 2004 Jan 11. Nat Immunol. 2004. PMID: 14716310

6

Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response.

Liberati NT, Fitzgerald KA, Kim DH, Feinbaum R, Golenbock DT, Ausubel FM. Liberati NT, et al. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6593-8. doi: 10.1073/pnas.0308625101. Proc Natl Acad Sci U S A. 2004. PMID: 15123841 Free PMC article.

7

The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.

Björkbacka H, Fitzgerald KA, Huet F, Li X, Gregory JA, Lee MA, Ordija CM, Dowley NE, Golenbock DT, Freeman MW. Björkbacka H, et al. Physiol Genomics. 2004 Nov 17;19(3):319-30. doi: 10.1152/physiolgenomics.00128.2004. Epub 2004 Sep 14. Physiol Genomics. 2004. PMID: 15367722 Free article.

8

Endotoxin recognition and signal transduction by the TLR4/MD2-complex.

Fitzgerald KA, Rowe DC, Golenbock DT. Fitzgerald KA, et al. Microbes Infect. 2004 Dec;6(15):1361-7. doi: 10.1016/j.micinf.2004.08.015. Microbes Infect. 2004. PMID: 15596121 Free article. Review.

9

The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.

Schoenemeyer A, Barnes BJ, Mancl ME, Latz E, Goutagny N, Pitha PM, Fitzgerald KA, Golenbock DT. Schoenemeyer A, et al. J Biol Chem. 2005 Apr 29;280(17):17005-12. doi: 10.1074/jbc.M412584200. Epub 2005 Jan 28. J Biol Chem. 2005. PMID: 15695821 Free article.

10

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

Rothenfusser S, Goutagny N, DiPerna G, Gong M, Monks BG, Schoenemeyer A, Yamamoto M, Akira S, Fitzgerald KA. Rothenfusser S, et al. J Immunol. 2005 Oct 15;175(8):5260-8. doi: 10.4049/jimmunol.175.8.5260. J Immunol. 2005. PMID: 16210631

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