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Let-7i-5p represses brite adipocyte function in mice and humans.
Giroud M, Karbiener M, Pisani DF, Ghandour RA, Beranger GE, Niemi T, Taittonen M, Nuutila P, Virtanen KA, Langin D, Scheideler M, Amri EZ. Giroud M, et al. Among authors: taittonen m. Sci Rep. 2016 Jun 27;6:28613. doi: 10.1038/srep28613. Sci Rep. 2016. PMID: 27345691 Free PMC article.
Functional brown adipose tissue in healthy adults.
Virtanen KA, Lidell ME, Orava J, Heglind M, Westergren R, Niemi T, Taittonen M, Laine J, Savisto NJ, Enerbäck S, Nuutila P. Virtanen KA, et al. Among authors: taittonen m. N Engl J Med. 2009 Apr 9;360(15):1518-25. doi: 10.1056/NEJMoa0808949. N Engl J Med. 2009. PMID: 19357407 Free article. Clinical Trial.
Human obesity is characterized by defective fat storage and enhanced muscle fatty acid oxidation, and trimetazidine gradually counteracts these abnormalities.
Bucci M, Borra R, Någren K, Maggio R, Tuunanen H, Oikonen V, Del Ry S, Viljanen T, Taittonen M, Rigazio S, Giannessi D, Parkkola R, Knuuti J, Nuutila P, Iozzo P. Bucci M, et al. Among authors: taittonen m. Am J Physiol Endocrinol Metab. 2011 Jul;301(1):E105-12. doi: 10.1152/ajpendo.00680.2010. Epub 2011 Apr 19. Am J Physiol Endocrinol Metab. 2011. PMID: 21505146 Free article. Clinical Trial.
Trimetazidine reduces endogenous free fatty acid oxidation and improves myocardial efficiency in obese humans.
Bucci M, Borra R, Någren K, Pärkkä JP, Del Ry S, Maggio R, Tuunanen H, Viljanen T, Cabiati M, Rigazio S, Taittonen M, Pagotto U, Parkkola R, Opie LH, Nuutila P, Knuuti J, Iozzo P. Bucci M, et al. Among authors: taittonen m. Cardiovasc Ther. 2012 Dec;30(6):333-41. doi: 10.1111/j.1755-5922.2011.00275.x. Epub 2011 Jul 31. Cardiovasc Ther. 2012. PMID: 21884010 Free article.
Visfatin expression analysis in association with recruitment and activation of human and rodent brown and brite adipocytes.
Pisani DF, Dumortier O, Beranger GE, Casamento V, Ghandour RA, Giroud M, Gautier N, Balaguer T, Chambard JC, Virtanen KA, Nuutila P, Niemi T, Taittonen M, Van Obberghen E, Hinault C, Amri EZ. Pisani DF, et al. Among authors: taittonen m. Adipocyte. 2015 Dec 9;5(2):186-95. doi: 10.1080/21623945.2015.1122854. eCollection 2016 Apr-Jun. Adipocyte. 2015. PMID: 27386154 Free PMC article.
miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function.
Giroud M, Pisani DF, Karbiener M, Barquissau V, Ghandour RA, Tews D, Fischer-Posovszky P, Chambard JC, Knippschild U, Niemi T, Taittonen M, Nuutila P, Wabitsch M, Herzig S, Virtanen KA, Langin D, Scheideler M, Amri EZ. Giroud M, et al. Among authors: taittonen m. Mol Metab. 2016 Jun 15;5(8):615-625. doi: 10.1016/j.molmet.2016.06.005. eCollection 2016 Aug. Mol Metab. 2016. PMID: 27656399 Free PMC article.
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