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Can combining different risk interventions into a single formulation contribute to improved cardiovascular disease risk reduction? Rationale and design for an international, open-label program to assess the effectiveness of a single pill (amlodipine/atorvastatin) to attain recommended target levels for blood pressure and lipids (The JEWEL Program).
Hobbs FD, Gensini G, Mancini GB, Manolis AJ, Bauer B, Böhler S, Genest J, Feldman R, Harvey P, Jenssen TG, Metcalfe M, da Silva PM; JEWEL Study Group. Hobbs FD, et al. Among authors: genest j. Int J Cardiol. 2006 Jun 16;110(2):242-50. doi: 10.1016/j.ijcard.2005.10.017. Epub 2005 Dec 9. Int J Cardiol. 2006. PMID: 16338012
Rationale, design and baseline characteristics of a large, simple, randomized trial of combined folic acid and vitamins B6 and B12 in high-risk patients: the Heart Outcomes Prevention Evaluation (HOPE)-2 trial.
Lonn E, Held C, Arnold JM, Probstfield J, McQueen M, Micks M, Pogue J, Sheridan P, Bosch J, Genest J, Yusuf S; HOPE-2 Investigators. Lonn E, et al. Among authors: genest j. Can J Cardiol. 2006 Jan;22(1):47-53. doi: 10.1016/s0828-282x(06)70238-0. Can J Cardiol. 2006. PMID: 16450017 Free PMC article. Clinical Trial.
987 results