Abbas T - Search Results

1

Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.

Benamar M, Guessous F, Du K, Corbett P, Obeid J, Gioeli D, Slingluff CL Jr, Abbas T. Benamar M, et al. Among authors: abbas t. EBioMedicine. 2016 Aug;10:85-100. doi: 10.1016/j.ebiom.2016.06.023. Epub 2016 Jun 16. EBioMedicine. 2016. PMID: 27333051 Free PMC article.

2

PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.

Abbas T, Sivaprasad U, Terai K, Amador V, Pagano M, Dutta A. Abbas T, et al. Genes Dev. 2008 Sep 15;22(18):2496-506. doi: 10.1101/gad.1676108. Genes Dev. 2008. PMID: 18794347 Free PMC article.

3

p21 in cancer: intricate networks and multiple activities.

Abbas T, Dutta A. Abbas T, et al. Nat Rev Cancer. 2009 Jun;9(6):400-14. doi: 10.1038/nrc2657. Nat Rev Cancer. 2009. PMID: 19440234 Free PMC article. Review.

4

CRL4(Cdt2) E3 ubiquitin ligase monoubiquitinates PCNA to promote translesion DNA synthesis.

Terai K, Abbas T, Jazaeri AA, Dutta A. Terai K, et al. Among authors: abbas t. Mol Cell. 2010 Jan 15;37(1):143-9. doi: 10.1016/j.molcel.2009.12.018. Mol Cell. 2010. PMID: 20129063 Free PMC article.

5

CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation.

Abbas T, Shibata E, Park J, Jha S, Karnani N, Dutta A. Abbas T, et al. Mol Cell. 2010 Oct 8;40(1):9-21. doi: 10.1016/j.molcel.2010.09.014. Mol Cell. 2010. PMID: 20932471 Free PMC article.

6

CRL4Cdt2: master coordinator of cell cycle progression and genome stability.

Abbas T, Dutta A. Abbas T, et al. Cell Cycle. 2011 Jan 15;10(2):241-9. doi: 10.4161/cc.10.2.14530. Epub 2011 Jan 15. Cell Cycle. 2011. PMID: 21212733 Free PMC article. Review.

7

Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.

Shibata E, Abbas T, Huang X, Wohlschlegel JA, Dutta A. Shibata E, et al. Among authors: abbas t. Mol Cell Biol. 2011 Aug;31(15):3136-45. doi: 10.1128/MCB.05496-11. Epub 2011 May 31. Mol Cell Biol. 2011. PMID: 21628527 Free PMC article.

8

CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration.

Abbas T, Mueller AC, Shibata E, Keaton M, Rossi M, Dutta A. Abbas T, et al. Mol Cell. 2013 Mar 28;49(6):1147-58. doi: 10.1016/j.molcel.2013.02.003. Epub 2013 Mar 7. Mol Cell. 2013. PMID: 23478445 Free PMC article.

9

Regulation of TGF-β signaling, exit from the cell cycle, and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2.

Abbas T, Keaton M, Dutta A. Abbas T, et al. Cell Cycle. 2013 Jul 15;12(14):2175-82. doi: 10.4161/cc.25314. Cell Cycle. 2013. PMID: 23892434 Free PMC article.

10

Degradation of p12 subunit by CRL4Cdt2 E3 ligase inhibits fork progression after DNA damage.

Terai K, Shibata E, Abbas T, Dutta A. Terai K, et al. Among authors: abbas t. J Biol Chem. 2013 Oct 18;288(42):30509-30514. doi: 10.1074/jbc.C113.505586. Epub 2013 Sep 10. J Biol Chem. 2013. PMID: 24022480 Free PMC article.

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