Sasabe H - Search Results

1

Erratum for Sasabe et al., Antitubercular Agent Delamanid and Metabolites as Substrates and Inhibitors of ABC and Solute Carrier Transporters.

Sasabe H, Shimokawa Y, Shibata M, Hashizume K, Hamasako Y, Ohzone Y, Kashiyama E, Umehara K. Sasabe H, et al. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4431. doi: 10.1128/AAC.01094-16. Print 2016 Jul. Antimicrob Agents Chemother. 2016. PMID: 27325820 Free PMC article. No abstract available.

2

Antitubercular Agent Delamanid and Metabolites as Substrates and Inhibitors of ABC and Solute Carrier Transporters.

Sasabe H, Shimokawa Y, Shibata M, Hashizume K, Hamasako Y, Ohzone Y, Kashiyama E, Umehara K. Sasabe H, et al. Antimicrob Agents Chemother. 2016 May 23;60(6):3497-508. doi: 10.1128/AAC.03049-15. Print 2016 Jun. Antimicrob Agents Chemother. 2016. PMID: 27021329 Free PMC article.

3

Prediction of Human Pharmacokinetic Profiles of the Antituberculosis Drug Delamanid from Nonclinical Data: Potential Therapeutic Value against Extrapulmonary Tuberculosis.

Shibata M, Masuda M, Sasahara K, Sasabe H, Sasaki T, Kim S, Takeuchi K, Umehara K, Kashiyama E. Shibata M, et al. Among authors: sasabe h. Antimicrob Agents Chemother. 2021 Jul 16;65(8):e0257120. doi: 10.1128/AAC.02571-20. Epub 2021 Jul 16. Antimicrob Agents Chemother. 2021. PMID: 34097484 Free PMC article.

4

Absorption, distribution and excretion of the anti-tuberculosis drug delamanid in rats: Extensive tissue distribution suggests potential therapeutic value for extrapulmonary tuberculosis.

Shibata M, Shimokawa Y, Sasahara K, Yoda N, Sasabe H, Suzuki M, Umehara K. Shibata M, et al. Among authors: sasabe h. Biopharm Drug Dispos. 2017 May;38(4):301-312. doi: 10.1002/bdd.2064. Epub 2017 Mar 8. Biopharm Drug Dispos. 2017. PMID: 28092695

5

In vitro evaluations for pharmacokinetic drug-drug interactions of a novel serotonin-dopamine activity modulator, brexpiprazole.

Sasabe H, Koga T, Furukawa M, Matsunaga M, Sasahara K, Hashizume K, Oozone Y, Amunom I, Torii M, Umehara K, Kashiyama E, Takeuchi K. Sasabe H, et al. Xenobiotica. 2021 May;51(5):522-535. doi: 10.1080/00498254.2021.1897898. Epub 2021 Mar 11. Xenobiotica. 2021. PMID: 33663326

6

Predicting drug metabolism and pharmacokinetics features of in-house compounds by a hybrid machine-learning model.

Sasahara K, Shibata M, Sasabe H, Suzuki T, Takeuchi K, Umehara K, Kashiyama E. Sasahara K, et al. Among authors: sasabe h. Drug Metab Pharmacokinet. 2021 Aug;39:100395. doi: 10.1016/j.dmpk.2021.100395. Epub 2021 Apr 20. Drug Metab Pharmacokinet. 2021. PMID: 33991751

7

Feature importance of machine learning prediction models shows structurally active part and important physicochemical features in drug design.

Sasahara K, Shibata M, Sasabe H, Suzuki T, Takeuchi K, Umehara K, Kashiyama E. Sasahara K, et al. Among authors: sasabe h. Drug Metab Pharmacokinet. 2021 Aug;39:100401. doi: 10.1016/j.dmpk.2021.100401. Epub 2021 May 3. Drug Metab Pharmacokinet. 2021. PMID: 34089983

8

Rebamipide does not interfere with the antitumor effect of radiotherapy or chemotherapy in human oral tumor-bearing nude mice.

Shibamori M, Sato M, Uematsu N, Nakashima T, Sato A, Yamamura Y, Sasabe H, Umehara K, Sakurai K. Shibamori M, et al. Among authors: sasabe h. J Pharmacol Sci. 2015 Sep;129(1):18-25. doi: 10.1016/j.jphs.2015.07.022. Epub 2015 Aug 4. J Pharmacol Sci. 2015. PMID: 26320673 Free article.

9

Pharmacokinetics and metabolism of brexpiprazole, a novel serotonin-dopamine activity modulator and its main metabolite in rat, monkey and human.

Sasabe H, Koga T, Furukawa M, Matsunaga M, Kaneko Y, Koyama N, Hirao Y, Akazawa H, Kawabata M, Kashiyama E, Takeuchi K. Sasabe H, et al. Xenobiotica. 2021 May;51(5):590-604. doi: 10.1080/00498254.2021.1890275. Epub 2021 Mar 9. Xenobiotica. 2021. PMID: 33685346

10

Mechanism of hydroxyl radical scavenging by rebamipide: identification of mono-hydroxylated rebamipide as a major reaction product.

Sakurai K, Sasabe H, Koga T, Konishi T. Sakurai K, et al. Among authors: sasabe h. Free Radic Res. 2004 May;38(5):487-94. doi: 10.1080/1071576042000209808. Free Radic Res. 2004. PMID: 15293556

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