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Page 1
Application of a phenotypic drug discovery strategy to identify biological and chemical starting points for inhibition of TSLP production in lung epithelial cells.
Orellana A, García-González V, López R, Pascual-Guiral S, Lozoya E, Díaz J, Casals D, Barrena A, Paris S, Andrés M, Segarra V, Vilella D, Malhotra R, Eastwood P, Planagumà A, Miralpeix M, Nueda A. Orellana A, et al. PLoS One. 2018 Jan 10;13(1):e0189247. doi: 10.1371/journal.pone.0189247. eCollection 2018. PLoS One. 2018. PMID: 29320511 Free PMC article.
Combined anti CXC receptors 1 and 2 therapy is a promising anti-inflammatory treatment for respiratory diseases by reducing neutrophil migration and activation.
Planagumà A, Domènech T, Pont M, Calama E, García-González V, López R, Aulí M, López M, Fonquerna S, Ramos I, de Alba J, Nueda A, Prats N, Segarra V, Miralpeix M, Lehner MD. Planagumà A, et al. Pulm Pharmacol Ther. 2015 Oct;34:37-45. doi: 10.1016/j.pupt.2015.08.002. Epub 2015 Aug 10. Pulm Pharmacol Ther. 2015. PMID: 26271598 Review.
Auraptene Boosts the Efficacy of the Tamoxifen Metabolites Endoxifen and 4-OH-Tamoxifen in a Chemoresistant ER+ Breast Cancer Model.
Pulido-Capiz A, Chimal-Vega B, Avila-Barrientos LP, Campos-Valenzuela A, Díaz-Molina R, Muñiz-Salazar R, Galindo-Hernández O, García-González V. Pulido-Capiz A, et al. Among authors: garcia gonzalez v. Pharmaceutics. 2024 Sep 6;16(9):1179. doi: 10.3390/pharmaceutics16091179. Pharmaceutics. 2024. PMID: 39339215 Free PMC article.
Identification of novel small molecule-based strategies of COL7A1 upregulation and readthrough activity for the treatment of recessive dystrophic epidermolysis bullosa.
Jover I, Ramos MC, Escámez MJ, Lozoya E, Tormo JR, de Prado-Verdún D, Mencía Á, Pont M, Puig C, Larraufie MH, Gutiérrez-Caballero C, Reyes F, Trincado JL, García-González V, Cerrato R, Andrés M, Crespo M, Vicente F, Godessart N, Genilloud O, Larcher F, Nueda A. Jover I, et al. Among authors: garcia gonzalez v. Sci Rep. 2024 Aug 16;14(1):18969. doi: 10.1038/s41598-024-67398-8. Sci Rep. 2024. PMID: 39152155 Free PMC article.
Tamoxifen metabolites treatment promotes ERα+ transition to triple negative phenotype in vitro, effects of LDL in chemoresistance.
Muñoz-Ayala A, Chimal-Vega B, Serafín-Higuera N, Galindo-Hernández O, Ramírez-Rosales G, Córdova-Guerrero I, Gómez-Lucas LF, García-González V. Muñoz-Ayala A, et al. Among authors: garcia gonzalez v. Biosci Rep. 2024 Aug 28;44(8):BSR20240444. doi: 10.1042/BSR20240444. Biosci Rep. 2024. PMID: 39034849 Free PMC article.
Low-Density Lipoproteins Increase Proliferation, Invasion, and Chemoresistance via an Exosome Autocrine Mechanism in MDA-MB-231 Chemoresistant Cells.
Castañeda-Sánchez CY, Chimal-Vega B, León-Gutiérrez R, Araiza-Robles AE, Serafín-Higuera N, Pulido-Capiz A, Rivero IA, Díaz-Molina R, Alatorre-Meda M, Rodríguez-Velázquez E, García-González V. Castañeda-Sánchez CY, et al. Among authors: garcia gonzalez v. Biomedicines. 2024 Mar 27;12(4):742. doi: 10.3390/biomedicines12040742. Biomedicines. 2024. PMID: 38672098 Free PMC article.
A Triazaspirane Derivative Inhibits Migration and Invasion in PC3 Prostate Cancer Cells.
Vasconcelos-Ulloa JJ, García-González V, Valdez-Salas B, Vázquez-Jiménez JG, Rivero-Espejel I, Díaz-Molina R, Galindo-Hernández O. Vasconcelos-Ulloa JJ, et al. Among authors: garcia gonzalez v. Molecules. 2023 Jun 2;28(11):4524. doi: 10.3390/molecules28114524. Molecules. 2023. PMID: 37299000 Free PMC article.
51 results