Scocchera E - Search Results

1

Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations.

Reeve SM, Scocchera E, Ferreira JJ, G-Dayanandan N, Keshipeddy S, Wright DL, Anderson AC. Reeve SM, et al. Among authors: scocchera e. J Med Chem. 2016 Jul 14;59(13):6493-500. doi: 10.1021/acs.jmedchem.6b00688. Epub 2016 Jun 28. J Med Chem. 2016. PMID: 27308944 Free PMC article.

2

Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens.

Scocchera E, Reeve SM, Keshipeddy S, Lombardo MN, Hajian B, Sochia AE, Alverson JB, Priestley ND, Anderson AC, Wright DL. Scocchera E, et al. ACS Med Chem Lett. 2016 May 5;7(7):692-6. doi: 10.1021/acsmedchemlett.6b00120. eCollection 2016 Jul 14. ACS Med Chem Lett. 2016. PMID: 27437079 Free PMC article.

3

Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis.

Hajian B, Scocchera E, Keshipeddy S, G-Dayanandan N, Shoen C, Krucinska J, Reeve S, Cynamon M, Anderson AC, Wright DL. Hajian B, et al. Among authors: scocchera e. PLoS One. 2016 Aug 31;11(8):e0161740. doi: 10.1371/journal.pone.0161740. eCollection 2016. PLoS One. 2016. PMID: 27580226 Free PMC article.

4

Toward new therapeutics for skin and soft tissue infections: propargyl-linked antifolates are potent inhibitors of MRSA and Streptococcus pyogenes.

Viswanathan K, Frey KM, Scocchera EW, Martin BD, Swain Iii PW, Alverson JB, Priestley ND, Anderson AC, Wright DL. Viswanathan K, et al. Among authors: scocchera ew. PLoS One. 2012;7(2):e29434. doi: 10.1371/journal.pone.0029434. Epub 2012 Feb 7. PLoS One. 2012. PMID: 22347365 Free PMC article.

5

MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.

Reeve SM, Scocchera EW, G-Dayanadan N, Keshipeddy S, Krucinska J, Hajian B, Ferreira J, Nailor M, Aeschlimann J, Wright DL, Anderson AC. Reeve SM, et al. Among authors: scocchera ew. Cell Chem Biol. 2016 Dec 22;23(12):1458-1467. doi: 10.1016/j.chembiol.2016.11.007. Epub 2016 Dec 8. Cell Chem Biol. 2016. PMID: 27939900 Free PMC article.

6

Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks.

G-Dayanandan N, Scocchera EW, Keshipeddy S, Jones HF, Anderson AC, Wright DL. G-Dayanandan N, et al. Among authors: scocchera ew. Org Lett. 2017 Jan 6;19(1):142-145. doi: 10.1021/acs.orglett.6b03438. Epub 2016 Dec 13. Org Lett. 2017. PMID: 27959567 Free PMC article.

7

Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents.

Hajian B, Scocchera E, Shoen C, Krucinska J, Viswanathan K, G-Dayanandan N, Erlandsen H, Estrada A, Mikušová K, Korduláková J, Cynamon M, Wright D. Hajian B, et al. Among authors: scocchera e. Cell Chem Biol. 2019 Jun 20;26(6):781-791.e6. doi: 10.1016/j.chembiol.2019.02.013. Epub 2019 Mar 28. Cell Chem Biol. 2019. PMID: 30930162 Free PMC article.

8

Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound.

Bond MJ, Bleiler M, Harrison LE, Scocchera EW, Nakanishi M, G-Dayanan N, Keshipeddy S, Rosenberg DW, Wright DL, Giardina C. Bond MJ, et al. Among authors: scocchera ew. Mol Cancer Res. 2018 Sep;16(9):1361-1372. doi: 10.1158/1541-7786.MCR-18-0178. Epub 2018 May 16. Mol Cancer Res. 2018. PMID: 29769406 Free PMC article.

9

Identification of novel compounds that enhance colon cancer cell sensitivity to inflammatory apoptotic ligands.

Chopra AS, Kuratnik A, Scocchera EW, Wright DL, Giardina C. Chopra AS, et al. Among authors: scocchera ew. Cancer Biol Ther. 2013 May;14(5):436-49. doi: 10.4161/cbt.23787. Epub 2013 Feb 1. Cancer Biol Ther. 2013. PMID: 23377828 Free PMC article.

10

Characterization of urban park litter pollution.

Pietrelli L, Vito SD, Lacolla E, Piozzi A, Scocchera E. Pietrelli L, et al. Among authors: scocchera e. Waste Manag. 2024 Dec 6;193:95-104. doi: 10.1016/j.wasman.2024.11.047. Online ahead of print. Waste Manag. 2024. PMID: 39644784

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