Wu H - Search Results

1

Discovery of 3-(3-(4-(1-Aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine (ARQ 092): An Orally Bioavailable, Selective, and Potent Allosteric AKT Inhibitor.

Lapierre JM, Eathiraj S, Vensel D, Liu Y, Bull CO, Cornell-Kennon S, Iimura S, Kelleher EW, Kizer DE, Koerner S, Makhija S, Matsuda A, Moussa M, Namdev N, Savage RE, Szwaya J, Volckova E, Westlund N, Wu H, Schwartz B. Lapierre JM, et al. Among authors: wu h. J Med Chem. 2016 Jul 14;59(13):6455-69. doi: 10.1021/acs.jmedchem.6b00619. Epub 2016 Jun 29. J Med Chem. 2016. PMID: 27305487

2

Discovery and optimization of a series of 3-(3-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amines: orally bioavailable, selective, and potent ATP-independent Akt inhibitors.

Ashwell MA, Lapierre JM, Brassard C, Bresciano K, Bull C, Cornell-Kennon S, Eathiraj S, France DS, Hall T, Hill J, Kelleher E, Khanapurkar S, Kizer D, Koerner S, Link J, Liu Y, Makhija S, Moussa M, Namdev N, Nguyen K, Nicewonger R, Palma R, Szwaya J, Tandon M, Uppalapati U, Vensel D, Volak LP, Volckova E, Westlund N, Wu H, Yang RY, Chan TC. Ashwell MA, et al. Among authors: wu h. J Med Chem. 2012 Jun 14;55(11):5291-310. doi: 10.1021/jm300276x. Epub 2012 May 31. J Med Chem. 2012. PMID: 22533986

3

Synthetic methods for the preparation of ARQ 501 (beta-Lapachone) human blood metabolites.

Yang RY, Kizer D, Wu H, Volckova E, Miao XS, Ali SM, Tandon M, Savage RE, Chan TC, Ashwell MA. Yang RY, et al. Among authors: wu h. Bioorg Med Chem. 2008 May 15;16(10):5635-43. doi: 10.1016/j.bmc.2008.03.073. Epub 2008 Apr 1. Bioorg Med Chem. 2008. PMID: 18424157

4

Identification of the in vitro metabolites of 3,4-dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; beta-lapachone) in whole blood.

Miao XS, Song P, Savage RE, Zhong C, Yang RY, Kizer D, Wu H, Volckova E, Ashwell MA, Supko JG, He X, Chan TC. Miao XS, et al. Among authors: wu h. Drug Metab Dispos. 2008 Apr;36(4):641-8. doi: 10.1124/dmd.107.018572. Epub 2008 Jan 7. Drug Metab Dispos. 2008. PMID: 18180274

5

Macamides and their synthetic analogs: evaluation of in vitro FAAH inhibition.

Wu H, Kelley CJ, Pino-Figueroa A, Vu HD, Maher TJ. Wu H, et al. Bioorg Med Chem. 2013 Sep 1;21(17):5188-97. doi: 10.1016/j.bmc.2013.06.034. Epub 2013 Jun 27. Bioorg Med Chem. 2013. PMID: 23891163

6

Discovery, Characterization, and Application of Broad-Spectrum Antimicrobial Peptide AtR905 from Aspergillus terreus as a Biocontrol Agent.

Zhao Y, Liu F, Lan X, Xu W, Dong W, Ke S, Wu H. Zhao Y, et al. Among authors: wu h. J Agric Food Chem. 2024 Dec 27. doi: 10.1021/acs.jafc.4c09294. Online ahead of print. J Agric Food Chem. 2024. PMID: 39729370

7

Identifying subgroups of ypN1 breast cancer patients who may exempt from axillary lymph node dissection after neoadjuvant chemotherapy: insights from a large cohort study.

Liu P, Liu D, Zhao C, Wei Y, Liu X, Cui H, Zhao X, Chang L, Lin S, Wu H, Ma X, Kang H, Wang M. Liu P, et al. Among authors: wu h. Breast Cancer. 2024 Dec 27. doi: 10.1007/s12282-024-01663-6. Online ahead of print. Breast Cancer. 2024. PMID: 39729291

8

Transgenic Schizochytrium as a Promising Oral Vaccine Carrier: Potential Application in the Aquaculture Industry.

Ma K, Deng L, Wu Y, Gao Y, Fan J, Wu H. Ma K, et al. Among authors: wu h. Mar Drugs. 2024 Dec 12;22(12):555. doi: 10.3390/md22120555. Mar Drugs. 2024. PMID: 39728130

9

Effect of Ankle-Foot Orthosis on Paretic Gastrocnemius and Tibialis Anterior Muscle Contraction of Stroke Survivors During Walking: A Pilot Study.

Liu W, Wu HD, Li YY, Zhu RT, Luo YY, Ling YT, Wang LK, Wang JF, Zheng YP, Ma CZ. Liu W, et al. Among authors: wu hd. Biosensors (Basel). 2024 Dec 4;14(12):595. doi: 10.3390/bios14120595. Biosensors (Basel). 2024. PMID: 39727859

10

Whole-Cell Vaccine Preparation Through Prussian Blue Nanoparticles-Elicited Immunogenic Cell Death and Loading in Gel Microneedles Patches.

Fu W, Li Q, Sheng J, Wu H, Ma M, Zhang Y. Fu W, et al. Among authors: wu h. Gels. 2024 Dec 19;10(12):838. doi: 10.3390/gels10120838. Gels. 2024. PMID: 39727596

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