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Inhibition of aldose reductase prevents colon cancer metastasis.
Tammali R, Reddy AB, Saxena A, Rychahou PG, Evers BM, Qiu S, Awasthi S, Ramana KV, Srivastava SK. Tammali R, et al. Among authors: saxena a. Carcinogenesis. 2011 Aug;32(8):1259-67. doi: 10.1093/carcin/bgr102. Epub 2011 Jun 3. Carcinogenesis. 2011. PMID: 21642355 Free PMC article.
Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells.
Tammali R, Saxena A, Srivastava SK, Ramana KV. Tammali R, et al. Among authors: saxena a. J Biol Chem. 2011 Jul 8;286(27):24089-100. doi: 10.1074/jbc.M111.219733. Epub 2011 May 16. J Biol Chem. 2011. PMID: 21576240 Free PMC article.
3,826 results