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Page 1
Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models.
Fischer W, Franke H, Krügel U, Müller H, Dinkel K, Lord B, Letavic MA, Henshall DC, Engel T. Fischer W, et al. Among authors: lord b. PLoS One. 2016 Jun 9;11(6):e0156468. doi: 10.1371/journal.pone.0156468. eCollection 2016. PLoS One. 2016. PMID: 27281030 Free PMC article.
Novel tetrahydroisoquinolines are histamine H3 antagonists and serotonin reuptake inhibitors.
Letavic MA, Keith JM, Jablonowski JA, Stocking EM, Gomez LA, Ly KS, Miller JM, Barbier AJ, Bonaventure P, Boggs JD, Wilson SJ, Miller KL, Lord B, McAllister HM, Tognarelli DJ, Wu J, Abad MC, Schubert C, Lovenberg TW, Carruthers NI. Letavic MA, et al. Among authors: lord b. Bioorg Med Chem Lett. 2007 Feb 15;17(4):1047-51. doi: 10.1016/j.bmcl.2006.11.036. Epub 2006 Nov 16. Bioorg Med Chem Lett. 2007. PMID: 17127059
Histamine H3 receptor antagonists: from target identification to drug leads.
Bonaventure P, Letavic M, Dugovic C, Wilson S, Aluisio L, Pudiak C, Lord B, Mazur C, Kamme F, Nishino S, Carruthers N, Lovenberg T. Bonaventure P, et al. Among authors: lord b. Biochem Pharmacol. 2007 Apr 15;73(8):1084-96. doi: 10.1016/j.bcp.2006.10.031. Epub 2006 Nov 3. Biochem Pharmacol. 2007. PMID: 17129577
Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.
Letavic MA, Stocking EM, Barbier AJ, Bonaventure P, Boggs JD, Lord B, Miller KL, Wilson SJ, Carruthers NI. Letavic MA, et al. Among authors: lord b. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4799-803. doi: 10.1016/j.bmcl.2007.06.061. Epub 2007 Jun 26. Bioorg Med Chem Lett. 2007. PMID: 17616397
Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor.
Barbier AJ, Aluisio L, Lord B, Qu Y, Wilson SJ, Boggs JD, Bonaventure P, Miller K, Fraser I, Dvorak L, Pudiak C, Dugovic C, Shelton J, Mazur C, Letavic MA, Carruthers NI, Lovenberg TW. Barbier AJ, et al. Among authors: lord b. Eur J Pharmacol. 2007 Dec 8;576(1-3):43-54. doi: 10.1016/j.ejphar.2007.08.009. Epub 2007 Aug 14. Eur J Pharmacol. 2007. PMID: 17765221
Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors.
Ly KS, Letavic MA, Keith JM, Miller JM, Stocking EM, Barbier AJ, Bonaventure P, Lord B, Jiang X, Boggs JD, Dvorak L, Miller KL, Nepomuceno D, Wilson SJ, Carruthers NI. Ly KS, et al. Among authors: lord b. Bioorg Med Chem Lett. 2008 Jan 1;18(1):39-43. doi: 10.1016/j.bmcl.2007.11.016. Epub 2007 Nov 13. Bioorg Med Chem Lett. 2008. PMID: 18060777
2-Aryloxymethylmorpholine histamine H(3) antagonists.
Letavic MA, Keith JM, Ly KS, Bonaventure P, Feinstein MA, Lord B, Miller KL, Motley ST, Nepomuceno D, Sutton SW, Carruthers NI. Letavic MA, et al. Among authors: lord b. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5796-9. doi: 10.1016/j.bmcl.2008.09.077. Epub 2008 Sep 24. Bioorg Med Chem Lett. 2008. PMID: 18922693
Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonists.
Stocking EM, Aluisio L, Atack JR, Bonaventure P, Carruthers NI, Dugovic C, Everson A, Fraser I, Jiang X, Leung P, Lord B, Ly KS, Morton KL, Nepomuceno D, Shah CR, Shelton J, Soyode-Johnson A, Letavic MA. Stocking EM, et al. Among authors: lord b. Bioorg Med Chem Lett. 2010 May 1;20(9):2755-60. doi: 10.1016/j.bmcl.2010.03.071. Epub 2010 Mar 20. Bioorg Med Chem Lett. 2010. PMID: 20382018
339 results