Rabbitts TH - Search Results

1

LMO2 and IL2RG synergize in thymocytes to mimic the evolution of SCID-X1 gene therapy-associated T-cell leukaemia.

Ruggero K, Al-Assar O, Chambers JS, Codrington R, Brend T, Rabbitts TH. Ruggero K, et al. Among authors: rabbitts th. Leukemia. 2016 Sep;30(9):1959-62. doi: 10.1038/leu.2016.116. Epub 2016 May 12. Leukemia. 2016. PMID: 27256700 Free PMC article. No abstract available.

2

Chromosomal translocations and leukaemia: a role for LMO2 in T cell acute leukaemia, in transcription and in erythropoiesis.

Rabbitts TH, Axelson H, Forster A, Grutz G, Lavenir I, Larson R, Osada H, Valge-Archer V, Wadman I, Warren A. Rabbitts TH, et al. Leukemia. 1997 Apr;11 Suppl 3:271-2. Leukemia. 1997. PMID: 9209362

3

LIM-only protein Lmo2 forms a protein complex with erythroid transcription factor GATA-1.

Osada H, Grutz GG, Axelson H, Forster A, Rabbitts TH. Osada H, et al. Among authors: rabbitts th. Leukemia. 1997 Apr;11 Suppl 3:307-12. Leukemia. 1997. PMID: 9209374

4

The invertor knock-in conditional chromosomal translocation mimic.

Forster A, Pannell R, Drynan LF, Codrington R, Daser A, Metzler M, Lobato MN, Rabbitts TH. Forster A, et al. Among authors: rabbitts th. Nat Methods. 2005 Jan;2(1):27-30. doi: 10.1038/nmeth727. Nat Methods. 2005. PMID: 15782166

5

The Ews-ERG fusion protein can initiate neoplasia from lineage-committed haematopoietic cells.

Codrington R, Pannell R, Forster A, Drynan LF, Daser A, Lobato N, Metzler M, Rabbitts TH. Codrington R, et al. Among authors: rabbitts th. PLoS Biol. 2005 Aug;3(8):e242. doi: 10.1371/journal.pbio.0030242. Epub 2005 Jun 28. PLoS Biol. 2005. PMID: 15974803 Free PMC article.

6

Chromosomal translocation engineering to recapitulate primary events of human cancer.

Forster A, Pannell R, Drynan L, Cano F, Chan N, Codrington R, Daser A, Lobato N, Metzler M, Nam CH, Rodriguez S, Tanaka T, Rabbitts T. Forster A, et al. Cold Spring Harb Symp Quant Biol. 2005;70:275-82. doi: 10.1101/sqb.2005.70.008. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869763

7

An antibody inhibitor of the LMO2-protein complex blocks its normal and tumorigenic functions.

Nam CH, Lobato MN, Appert A, Drynan LF, Tanaka T, Rabbitts TH. Nam CH, et al. Among authors: rabbitts th. Oncogene. 2008 Aug 21;27(36):4962-8. doi: 10.1038/onc.2008.130. Epub 2008 Apr 28. Oncogene. 2008. PMID: 18438427

8

The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal.

McCormack MP, Young LF, Vasudevan S, de Graaf CA, Codrington R, Rabbitts TH, Jane SM, Curtis DJ. McCormack MP, et al. Among authors: rabbitts th. Science. 2010 Feb 12;327(5967):879-83. doi: 10.1126/science.1182378. Epub 2010 Jan 21. Science. 2010. PMID: 20093438

9

Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex.

Sewell H, Tanaka T, El Omari K, Mancini EJ, Cruz A, Fernandez-Fuentes N, Chambers J, Rabbitts TH. Sewell H, et al. Among authors: rabbitts th. Sci Rep. 2014 Jan 10;4:3643. doi: 10.1038/srep03643. Sci Rep. 2014. PMID: 24407558 Free PMC article.

10

Sequential gene targeting to make chimeric tumor models with de novo chromosomal abnormalities.

Chambers JS, Tanaka T, Brend T, Ali H, Geisler NJ, Khazin L, Cigudosa JC, Dear TN, MacLennan K, Rabbitts TH. Chambers JS, et al. Among authors: rabbitts th. Cancer Res. 2014 Mar 1;74(5):1588-97. doi: 10.1158/0008-5472.CAN-13-1783. Epub 2014 Jan 13. Cancer Res. 2014. PMID: 24419086 Free article.

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