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Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma.
Kodama T, Newberg JY, Kodama M, Rangel R, Yoshihara K, Tien JC, Parsons PH, Wu H, Finegold MJ, Copeland NG, Jenkins NA. Kodama T, et al. Among authors: rangel r. Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):E3384-93. doi: 10.1073/pnas.1606876113. Epub 2016 May 31. Proc Natl Acad Sci U S A. 2016. PMID: 27247392 Free PMC article.
An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment.
Mintz PJ, Cardó-Vila M, Ozawa MG, Hajitou A, Rangel R, Guzman-Rojas L, Christianson DR, Arap MA, Giordano RJ, Souza GR, Easley J, Salameh A, Oliviero S, Brentani RR, Koivunen E, Arap W, Pasqualini R. Mintz PJ, et al. Among authors: rangel r. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2182-7. doi: 10.1073/pnas.0807543105. Epub 2009 Jan 23. Proc Natl Acad Sci U S A. 2009. PMID: 19168626 Free PMC article.
Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment.
Guzman-Rojas L, Rangel R, Salameh A, Edwards JK, Dondossola E, Kim YG, Saghatelian A, Giordano RJ, Kolonin MG, Staquicini FI, Koivunen E, Sidman RL, Arap W, Pasqualini R. Guzman-Rojas L, et al. Among authors: rangel r. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1637-42. doi: 10.1073/pnas.1120790109. Epub 2012 Jan 17. Proc Natl Acad Sci U S A. 2012. PMID: 22307623 Free PMC article.
In vivo loss-of-function screens identify KPNB1 as a new druggable oncogene in epithelial ovarian cancer.
Kodama M, Kodama T, Newberg JY, Katayama H, Kobayashi M, Hanash SM, Yoshihara K, Wei Z, Tien JC, Rangel R, Hashimoto K, Mabuchi S, Sawada K, Kimura T, Copeland NG, Jenkins NA. Kodama M, et al. Among authors: rangel r. Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):E7301-E7310. doi: 10.1073/pnas.1705441114. Epub 2017 Aug 15. Proc Natl Acad Sci U S A. 2017. PMID: 28811376 Free PMC article.
Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression.
Aiderus A, Newberg JY, Guzman-Rojas L, Contreras-Sandoval AM, Meshey AL, Jones DJ, Amaya-Manzanares F, Rangel R, Ward JM, Lee SC, Ban KH, Rogers K, Rogers SM, Selvanesan L, McNoe LA, Copeland NG, Jenkins NA, Tsai KY, Black MA, Mann KM, Mann MB. Aiderus A, et al. Among authors: rangel r. PLoS Genet. 2021 Aug 16;17(8):e1009094. doi: 10.1371/journal.pgen.1009094. eCollection 2021 Aug. PLoS Genet. 2021. PMID: 34398873 Free PMC article.
159 results