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Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection.
Densham RM, Garvin AJ, Stone HR, Strachan J, Baldock RA, Daza-Martin M, Fletcher A, Blair-Reid S, Beesley J, Johal B, Pearl LH, Neely R, Keep NH, Watts FZ, Morris JR. Densham RM, et al. Among authors: fletcher a. Nat Struct Mol Biol. 2016 Jul;23(7):647-55. doi: 10.1038/nsmb.3236. Epub 2016 May 30. Nat Struct Mol Biol. 2016. PMID: 27239795 Free PMC article.
PTTG and PBF Functionally Interact with p53 and Predict Overall Survival in Head and Neck Cancer.
Read ML, Modasia B, Fletcher A, Thompson RJ, Brookes K, Rae PC, Nieto HR, Poole VL, Roberts S, Campbell MJ, Boelaert K, Turnell AS, Smith VE, Mehanna H, McCabe CJ. Read ML, et al. Among authors: fletcher a. Cancer Res. 2018 Oct 15;78(20):5863-5876. doi: 10.1158/0008-5472.CAN-18-0855. Epub 2018 Aug 28. Cancer Res. 2018. PMID: 30154144 Free PMC article.
Recurrence of Papillary Thyroid Cancer: A Systematic Appraisal of Risk Factors.
Nieto HR, Thornton CEM, Brookes K, Nobre de Menezes A, Fletcher A, Alshahrani M, Kocbiyik M, Sharma N, Boelaert K, Cazier JB, Mehanna H, Smith VE, Read ML, McCabe CJ. Nieto HR, et al. Among authors: fletcher a. J Clin Endocrinol Metab. 2022 Apr 19;107(5):1392-1406. doi: 10.1210/clinem/dgab836. J Clin Endocrinol Metab. 2022. PMID: 34791326 Free PMC article.
Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer.
Read ML, Fong JC, Modasia B, Fletcher A, Imruetaicharoenchoke W, Thompson RJ, Nieto H, Reynolds JJ, Bacon A, Mallick U, Hackshaw A, Watkinson JC, Boelaert K, Turnell AS, Smith VE, McCabe CJ. Read ML, et al. Among authors: fletcher a. Oncogene. 2017 Sep 14;36(37):5296-5308. doi: 10.1038/onc.2017.154. Epub 2017 May 15. Oncogene. 2017. PMID: 28504713 Free PMC article.
Functional consequences of the first reported mutations of the proto-oncogene PTTG1IP/PBF.
Imruetaicharoenchoke W, Fletcher A, Lu W, Watkins RJ, Modasia B, Poole VL, Nieto HR, Thompson RJ, Boelaert K, Read ML, Smith VE, McCabe CJ. Imruetaicharoenchoke W, et al. Among authors: fletcher a. Endocr Relat Cancer. 2017 Sep;24(9):459-474. doi: 10.1530/ERC-16-0340. Epub 2017 Jul 4. Endocr Relat Cancer. 2017. PMID: 28676500 Free PMC article.
Dimerization of the Sodium/Iodide Symporter.
Thompson RJ, Fletcher A, Brookes K, Nieto H, Alshahrani MM, Mueller JW, Fine NHF, Hodson DJ, Boelaert K, Read ML, Smith VE, McCabe CJ. Thompson RJ, et al. Among authors: fletcher a. Thyroid. 2019 Oct;29(10):1485-1498. doi: 10.1089/thy.2019.0034. Epub 2019 Aug 30. Thyroid. 2019. PMID: 31310151 Free PMC article.
Targeting Novel Sodium Iodide Symporter Interactors ADP-Ribosylation Factor 4 and Valosin-Containing Protein Enhances Radioiodine Uptake.
Fletcher A, Read ML, Thornton CEM, Larner DP, Poole VL, Brookes K, Nieto HR, Alshahrani M, Thompson RJ, Lavery GG, Landa I, Fagin JA, Campbell MJ, Boelaert K, Turnell AS, Smith VE, McCabe CJ. Fletcher A, et al. Cancer Res. 2020 Jan 1;80(1):102-115. doi: 10.1158/0008-5472.CAN-19-1957. Epub 2019 Oct 31. Cancer Res. 2020. PMID: 31672844 Free PMC article.
Myocardial Fibroblast Activation After Acute Myocardial Infarction: A Positron Emission Tomography and Magnetic Resonance Study.
Barton AK, Craig NJ, Loganath K, Joshi S, Tsampasian V, Mahendran M, Lenell J, Tzolos E, Singh T, Whittington B, Nash J, Williams MC, van Beek EJR, MacAskill MG, Berkeley B, Vezaides S, Brittan M, Baker AH, Sellers S, Fletcher A, Clark T, Waight C, Slart RHJA, Berman D, Dey D, Slomka P, Newby DE, Dweck MR. Barton AK, et al. Among authors: fletcher a. J Am Coll Cardiol. 2024 Nov 26:S0735-1097(24)10315-4. doi: 10.1016/j.jacc.2024.10.103. Online ahead of print. J Am Coll Cardiol. 2024. PMID: 39772364
1,794 results