Qian H - Search Results

1

Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection.

Gong X, Qian H, Zhou X, Wu J, Wan T, Cao P, Huang W, Zhao X, Wang X, Wang P, Shi Y, Gao GF, Zhou Q, Yan N. Gong X, et al. Among authors: qian h. Cell. 2016 Jun 2;165(6):1467-1478. doi: 10.1016/j.cell.2016.05.022. Epub 2016 May 26. Cell. 2016. PMID: 27238017 Free PMC article.

2

Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition.

Gong X, Li J, Shao W, Wu J, Qian H, Ren R, Espenshade P, Yan N. Gong X, et al. Among authors: qian h. Cell Res. 2015 Apr;25(4):401-11. doi: 10.1038/cr.2015.32. Epub 2015 Mar 13. Cell Res. 2015. PMID: 25771684 Free PMC article.

3

Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization.

Gong X, Qian H, Shao W, Li J, Wu J, Liu JJ, Li W, Wang HW, Espenshade P, Yan N. Gong X, et al. Among authors: qian h. Cell Res. 2016 Nov;26(11):1197-1211. doi: 10.1038/cr.2016.123. Epub 2016 Nov 4. Cell Res. 2016. PMID: 27811944 Free PMC article.

4

Structure of the Human Lipid Exporter ABCA1.

Qian H, Zhao X, Cao P, Lei J, Yan N, Gong X. Qian H, et al. Cell. 2017 Jun 15;169(7):1228-1239.e10. doi: 10.1016/j.cell.2017.05.020. Epub 2017 Jun 8. Cell. 2017. PMID: 28602350 Free article.

5

Structural basis for the recognition of Sonic Hedgehog by human Patched1.

Gong X, Qian H, Cao P, Zhao X, Zhou Q, Lei J, Yan N. Gong X, et al. Among authors: qian h. Science. 2018 Aug 10;361(6402):eaas8935. doi: 10.1126/science.aas8935. Epub 2018 Jun 28. Science. 2018. PMID: 29954986

6

Human SEIPIN Binds Anionic Phospholipids.

Yan R, Qian H, Lukmantara I, Gao M, Du X, Yan N, Yang H. Yan R, et al. Among authors: qian h. Dev Cell. 2018 Oct 22;47(2):248-256.e4. doi: 10.1016/j.devcel.2018.09.010. Epub 2018 Oct 4. Dev Cell. 2018. PMID: 30293840 Free article.

7

Purification and Characterization of Human Niemann-Pick C1 Protein.

Gong X, Qian H. Gong X, et al. Among authors: qian h. Methods Mol Biol. 2019;1949:257-267. doi: 10.1007/978-1-4939-9136-5_18. Methods Mol Biol. 2019. PMID: 30790261

8

Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm.

Qian H, Cao P, Hu M, Gao S, Yan N, Gong X. Qian H, et al. Nat Commun. 2019 May 24;10(1):2320. doi: 10.1038/s41467-019-10234-9. Nat Commun. 2019. PMID: 31127104 Free PMC article.

9

Structure and mechanism of human diacylglycerol O-acyltransferase 1.

Wang L, Qian H, Nian Y, Han Y, Ren Z, Zhang H, Hu L, Prasad BVV, Laganowsky A, Yan N, Zhou M. Wang L, et al. Among authors: qian h. Nature. 2020 May;581(7808):329-332. doi: 10.1038/s41586-020-2280-2. Epub 2020 May 13. Nature. 2020. PMID: 32433610 Free PMC article.

10

Structural basis for catalysis and substrate specificity of human ACAT1.

Qian H, Zhao X, Yan R, Yao X, Gao S, Sun X, Du X, Yang H, Wong CCL, Yan N. Qian H, et al. Nature. 2020 May;581(7808):333-338. doi: 10.1038/s41586-020-2290-0. Epub 2020 May 13. Nature. 2020. PMID: 32433614

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