Elsaadi MT - Search Results

1

Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines.

Abdel Gawad NM, Amin NH, Elsaadi MT, Mohamed FMM, Angeli A, De Luca V, Capasso C, Supuran CT. Abdel Gawad NM, et al. Among authors: elsaadi mt. Bioorg Med Chem. 2016 Jul 1;24(13):3043-3051. doi: 10.1016/j.bmc.2016.05.016. Epub 2016 May 12. Bioorg Med Chem. 2016. PMID: 27234893

2

Synthesis, anti-inflammatory and ulcerogenicity studies of some substituted pyrimido[1,6-a]azepine derivatives.

El-Sayed NA, Awadallah FM, Ibrahim NA, El-Saadi MT. El-Sayed NA, et al. Eur J Med Chem. 2010 Jul;45(7):3147-54. doi: 10.1016/j.ejmech.2010.04.005. Epub 2010 Apr 14. Eur J Med Chem. 2010. PMID: 20444529

3

Design, synthesis and analgesic/anti-inflammatory evaluation of novel diarylthiazole and diarylimidazole derivatives towards selective COX-1 inhibitors with better gastric profile.

Abdelazeem AH, El-Saadi MT, Safi El-Din AG, Omar HA, El-Moghazy SM. Abdelazeem AH, et al. Bioorg Med Chem. 2017 Jan 15;25(2):665-676. doi: 10.1016/j.bmc.2016.11.037. Epub 2016 Nov 23. Bioorg Med Chem. 2017. PMID: 27916468

4

Novel diphenylthiazole derivatives with multi-target mechanism: Synthesis, docking study, anticancer and anti-inflammatory activities.

Abdelazeem AH, El-Saadi MT, Said EG, Youssif BGM, Omar HA, El-Moghazy SM. Abdelazeem AH, et al. Bioorg Chem. 2017 Dec;75:127-138. doi: 10.1016/j.bioorg.2017.09.009. Epub 2017 Sep 12. Bioorg Chem. 2017. PMID: 28938224

5

Design, synthesis and anticancer evaluation of novel spirobenzo[h]chromene and spirochromane derivatives with dual EGFR and B-RAF inhibitory activities.

Abdelatef SA, El-Saadi MT, Amin NH, Abdelazeem AH, Omar HA, Abdellatif KRA. Abdelatef SA, et al. Eur J Med Chem. 2018 Apr 25;150:567-578. doi: 10.1016/j.ejmech.2018.03.001. Epub 2018 Mar 5. Eur J Med Chem. 2018. PMID: 29549841

6

Anti-inflammatory indomethacin analogs endowed with preferential COX-2 inhibitory activity.

Amin NH, El-Saadi MT, Hefny AA, Abdelazeem AH, Elshemy HA, Abdellatif KR. Amin NH, et al. Future Med Chem. 2018 Nov;10(21):2521-2535. doi: 10.4155/fmc-2018-0224. Epub 2018 Dec 6. Future Med Chem. 2018. PMID: 30518260

7

New substituted pyrazole derivatives targeting COXs as potential safe anti-inflammatory agents.

Abdellatif KR, El-Saadi MT, Elzayat SG, Amin NH. Abdellatif KR, et al. Future Med Chem. 2019 Aug;11(15):1871-1882. doi: 10.4155/fmc-2018-0548. Future Med Chem. 2019. PMID: 31517535

8

Discovery of novel urea-diarylpyrazole hybrids as dual COX-2/sEH inhibitors with improved anti-inflammatory activity and highly reduced cardiovascular risks.

Abdelazeem AH, Safi El-Din AG, Abdel-Fattah MM, Amin NH, El-Moghazy SM, El-Saadi MT. Abdelazeem AH, et al. Eur J Med Chem. 2020 Nov 1;205:112662. doi: 10.1016/j.ejmech.2020.112662. Epub 2020 Jul 24. Eur J Med Chem. 2020. PMID: 32763463

9

Design, synthesis and molecular modeling studies of 2-styrylquinazoline derivatives as EGFR inhibitors and apoptosis inducers.

Amin NH, Elsaadi MT, Zaki SS, Abdel-Rahman HM. Amin NH, et al. Among authors: elsaadi mt. Bioorg Chem. 2020 Dec;105:104358. doi: 10.1016/j.bioorg.2020.104358. Epub 2020 Oct 8. Bioorg Chem. 2020. PMID: 33074119

10

Validated green chromatographic methods for determination of amlodipine and celecoxib in presence of methylacetophenone.

Z Sharkawi MM, Mohamed NR, El-Saadi MT, Amin NH. Z Sharkawi MM, et al. Bioanalysis. 2021 Jun;13(12):969-983. doi: 10.4155/bio-2021-0040. Epub 2021 Jun 4. Bioanalysis. 2021. PMID: 34085866

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