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Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons.
Huang HS, Allen JA, Mabb AM, King IF, Miriyala J, Taylor-Blake B, Sciaky N, Dutton JW Jr, Lee HM, Chen X, Jin J, Bridges AS, Zylka MJ, Roth BL, Philpot BD. Huang HS, et al. Among authors: philpot bd. Nature. 2011 Dec 21;481(7380):185-9. doi: 10.1038/nature10726. Nature. 2011. PMID: 22190039 Free PMC article.
Transsynaptic signaling by activity-dependent cleavage of neuroligin-1.
Peixoto RT, Kunz PA, Kwon H, Mabb AM, Sabatini BL, Philpot BD, Ehlers MD. Peixoto RT, et al. Among authors: philpot bd. Neuron. 2012 Oct 18;76(2):396-409. doi: 10.1016/j.neuron.2012.07.006. Epub 2012 Oct 17. Neuron. 2012. PMID: 23083741 Free PMC article.
Topoisomerases facilitate transcription of long genes linked to autism.
King IF, Yandava CN, Mabb AM, Hsiao JS, Huang HS, Pearson BL, Calabrese JM, Starmer J, Parker JS, Magnuson T, Chamberlain SJ, Philpot BD, Zylka MJ. King IF, et al. Among authors: philpot bd. Nature. 2013 Sep 5;501(7465):58-62. doi: 10.1038/nature12504. Epub 2013 Aug 28. Nature. 2013. PMID: 23995680 Free PMC article.
Zylka et al. reply.
Zylka MJ, Philpot BD, King IF. Zylka MJ, et al. Among authors: philpot bd. Nature. 2014 Aug 7;512(7512):E2. doi: 10.1038/nature13584. Nature. 2014. PMID: 25100485 Free PMC article. No abstract available.
Topoisomerase 1 inhibition reversibly impairs synaptic function.
Mabb AM, Kullmann PH, Twomey MA, Miriyala J, Philpot BD, Zylka MJ. Mabb AM, et al. Among authors: philpot bd. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17290-5. doi: 10.1073/pnas.1413204111. Epub 2014 Nov 17. Proc Natl Acad Sci U S A. 2014. PMID: 25404338 Free PMC article.
111 results