Feng Y - Search Results

1

Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors.

Zhao LH, Yin Y, Yang D, Liu B, Hou L, Wang X, Pal K, Jiang Y, Feng Y, Cai X, Dai A, Liu M, Wang MW, Melcher K, Xu HE. Zhao LH, et al. Among authors: feng y. J Biol Chem. 2016 Jul 15;291(29):15119-30. doi: 10.1074/jbc.M116.726620. Epub 2016 May 13. J Biol Chem. 2016. PMID: 27226600 Free PMC article.

2

Aromatic beta-amino-ketone derivatives as novel selective non-steroidal progesterone receptor antagonists.

Du Y, Li Q, Xiong B, Hui X, Wang X, Feng Y, Meng T, Hu D, Zhang D, Wang M, Shen J. Du Y, et al. Among authors: feng y. Bioorg Med Chem. 2010 Jun 15;18(12):4255-68. doi: 10.1016/j.bmc.2010.04.092. Epub 2010 May 24. Bioorg Med Chem. 2010. PMID: 20510622

3

V101L of human formyl peptide receptor 1 (FPR1) increases receptor affinity and augments the antagonism mediated by cyclosporins.

Zhou C, Zhou Y, Wang J, Feng Y, Wang H, Xue J, Chen Y, Ye RD, Wang MW. Zhou C, et al. Among authors: feng y. Biochem J. 2013 Apr 15;451(2):245-55. doi: 10.1042/BJ20121839. Biochem J. 2013. PMID: 23373827 Free PMC article.

4

High-throughput screening for GPR119 modulators identifies a novel compound with anti-diabetic efficacy in db/db mice.

Zhang M, Feng Y, Wang J, Zhao J, Li T, He M, Yang D, Nosjean O, Boutin J, Renard P, Wang MW. Zhang M, et al. Among authors: feng y. PLoS One. 2013 May 21;8(5):e63861. doi: 10.1371/journal.pone.0063861. Print 2013. PLoS One. 2013. PMID: 23704946 Free PMC article.

5

Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R).

Yang D, de Graaf C, Yang L, Song G, Dai A, Cai X, Feng Y, Reedtz-Runge S, Hanson MA, Yang H, Jiang H, Stevens RC, Wang MW. Yang D, et al. Among authors: feng y. J Biol Chem. 2016 Jun 17;291(25):12991-3004. doi: 10.1074/jbc.M116.721977. Epub 2016 Apr 8. J Biol Chem. 2016. PMID: 27059958 Free PMC article.

6

Design, synthesis, structure-activity relationships, and docking studies of pyrazole-containing derivatives as a novel series of potent glucagon receptor antagonists.

Shu S, Cai X, Li J, Feng Y, Dai A, Wang J, Yang D, Wang MW, Liu H. Shu S, et al. Among authors: feng y. Bioorg Med Chem. 2016 Jun 15;24(12):2852-63. doi: 10.1016/j.bmc.2016.04.053. Epub 2016 Apr 26. Bioorg Med Chem. 2016. PMID: 27161876

7

W2476 ameliorates β-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway.

Li T, Lin GY, Zhong L, Zhou Y, Wang J, Zhu Y, Feng Y, Cai XQ, Liu Q, Nosjean O, Boutin JA, Renard P, Yang DH, Wang MW. Li T, et al. Among authors: feng y. Acta Pharmacol Sin. 2017 Jul;38(7):1024-1037. doi: 10.1038/aps.2017.15. Epub 2017 May 15. Acta Pharmacol Sin. 2017. PMID: 28502980 Free PMC article.

8

Discovery of thiophene-containing biaryl amide derivatives as novel glucagon receptor antagonists.

Li J, Feng Y, Li H, Shu S, Dai A, Cai X, Wang J, Yang D, Ma D, Wang MW, Liu H. Li J, et al. Among authors: feng y. Chem Biol Drug Des. 2018 Jul;92(1):1241-1254. doi: 10.1111/cbdd.13184. Epub 2018 Apr 10. Chem Biol Drug Des. 2018. PMID: 29469980

9

A novel series of 4-methyl substituted pyrazole derivatives as potent glucagon receptor antagonists: Design, synthesis and evaluation of biological activities.

Shu S, Dai A, Wang J, Wang B, Feng Y, Li J, Cai X, Yang D, Ma D, Wang MW, Liu H. Shu S, et al. Among authors: feng y. Bioorg Med Chem. 2018 May 1;26(8):1896-1908. doi: 10.1016/j.bmc.2018.02.036. Epub 2018 Feb 22. Bioorg Med Chem. 2018. PMID: 29523469

10

Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism.

Lei S, Clydesdale L, Dai A, Cai X, Feng Y, Yang D, Liang YL, Koole C, Zhao P, Coudrat T, Christopoulos A, Wang MW, Wootten D, Sexton PM. Lei S, et al. Among authors: feng y. J Biol Chem. 2018 Jun 15;293(24):9370-9387. doi: 10.1074/jbc.RA118.003278. Epub 2018 May 1. J Biol Chem. 2018. PMID: 29717000 Free PMC article.

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