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Page 1
Epigenetic therapy as a novel approach for GFI136N-associated murine/human AML.
Botezatu L, Michel LC, Helness A, Vadnais C, Makishima H, Hönes JM, Robert F, Vassen L, Thivakaran A, Al-Matary Y, Lams RF, Schütte J, Giebel B, Görgens A, Heuser M, Medyouf H, Maciejewski J, Dührsen U, Möröy T, Khandanpour C. Botezatu L, et al. Among authors: medyouf h. Exp Hematol. 2016 Aug;44(8):713-726.e14. doi: 10.1016/j.exphem.2016.05.004. Epub 2016 May 20. Exp Hematol. 2016. PMID: 27216773 Free article.
Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization.
Schanda J, Lee CW, Wohlan K, Müller-Kuller U, Kunkel H, Coco IQ, Stein S, Metz A, Koch J, Lausen J, Platzbecker U, Medyouf H, Gohlke H, Heuser M, Eder M, Grez M, Scherr M, Wichmann C. Schanda J, et al. Among authors: medyouf h. Haematologica. 2017 May;102(5):e170-e174. doi: 10.3324/haematol.2016.161570. Epub 2017 Feb 2. Haematologica. 2017. PMID: 28154087 Free PMC article. No abstract available.
Myelodysplasia is in the niche: novel concepts and emerging therapies.
Bulycheva E, Rauner M, Medyouf H, Theurl I, Bornhäuser M, Hofbauer LC, Platzbecker U. Bulycheva E, et al. Among authors: medyouf h. Leukemia. 2015 Feb;29(2):259-68. doi: 10.1038/leu.2014.325. Epub 2014 Nov 14. Leukemia. 2015. PMID: 25394715 Free PMC article. Review.
MiR144/451 Expression Is Repressed by RUNX1 During Megakaryopoiesis and Disturbed by RUNX1/ETO.
Kohrs N, Kolodziej S, Kuvardina ON, Herglotz J, Yillah J, Herkt S, Piechatzek A, Salinas Riester G, Lingner T, Wichmann C, Bonig H, Seifried E, Platzbecker U, Medyouf H, Grez M, Lausen J. Kohrs N, et al. Among authors: medyouf h. PLoS Genet. 2016 Mar 18;12(3):e1005946. doi: 10.1371/journal.pgen.1005946. eCollection 2016 Mar. PLoS Genet. 2016. PMID: 26990877 Free PMC article.
Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure.
Mossner M, Jann JC, Wittig J, Nolte F, Fey S, Nowak V, Obländer J, Pressler J, Palme I, Xanthopoulos C, Boch T, Metzgeroth G, Röhl H, Witt SH, Dukal H, Klein C, Schmitt S, Gelß P, Platzbecker U, Balaian E, Fabarius A, Blum H, Schulze TJ, Meggendorfer M, Haferlach C, Trumpp A, Hofmann WK, Medyouf H, Nowak D. Mossner M, et al. Among authors: medyouf h. Blood. 2016 Sep 1;128(9):1246-59. doi: 10.1182/blood-2015-11-679167. Epub 2016 Jun 6. Blood. 2016. PMID: 27268087 Free article.
AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer.
Varga J, Nicolas A, Petrocelli V, Pesic M, Mahmoud A, Michels BE, Etlioglu E, Yepes D, Häupl B, Ziegler PK, Bankov K, Wild PJ, Wanninger S, Medyouf H, Farin HF, Tejpar S, Oellerich T, Ruland J, Siebel CW, Greten FR. Varga J, et al. Among authors: medyouf h. J Exp Med. 2020 Oct 5;217(10):e20191515. doi: 10.1084/jem.20191515. J Exp Med. 2020. PMID: 32749453 Free PMC article.
AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia.
Tirado-Gonzalez I, Descot A, Soetopo D, Nevmerzhitskaya A, Schäffer A, Kur IM, Czlonka E, Wachtel C, Tsoukala I, Müller L, Schäfer AL, Weitmann M, Dinse P, Alberto E, Buck MC, Landry JJ, Baying B, Slotta-Huspenina J, Roesler J, Harter PN, Kubasch AS, Meinel J, Elwakeel E, Strack E, Quang CT, Abdel-Wahab O, Schmitz M, Weigert A, Schmid T, Platzbecker U, Benes V, Ghysdael J, Bonig H, Götze KS, Rothlin CV, Ghosh S, Medyouf H. Tirado-Gonzalez I, et al. Among authors: medyouf h. Cancer Discov. 2021 Nov;11(11):2924-2943. doi: 10.1158/2159-8290.CD-20-1378. Epub 2021 Jun 8. Cancer Discov. 2021. PMID: 34103328 Free PMC article.
28 results