Yang YA - Search Results

1

Quantitation of TGF-β proteins in mouse tissues shows reciprocal changes in TGF-β1 and TGF-β3 in normal vs neoplastic mammary epithelium.

Flanders KC, Yang YA, Herrmann M, Chen J, Mendoza N, Mirza AM, Wakefield LM. Flanders KC, et al. Among authors: yang ya. Oncotarget. 2016 Jun 21;7(25):38164-38179. doi: 10.18632/oncotarget.9416. Oncotarget. 2016. PMID: 27203217 Free PMC article.

2

Biological responses to TGF-β in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression.

Kohn EA, Yang YA, Du Z, Nagano Y, Van Schyndle CM, Herrmann MA, Heldman M, Chen JQ, Stuelten CH, Flanders KC, Wakefield LM. Kohn EA, et al. Among authors: yang ya. Mol Cancer Res. 2012 Oct;10(10):1389-99. doi: 10.1158/1541-7786.MCR-12-0136-T. Epub 2012 Aug 9. Mol Cancer Res. 2012. PMID: 22878587 Free PMC article.

3

Effective chemoimmunotherapy with anti-TGFβ antibody and cyclophosphamide in a mouse model of breast cancer.

Chen X, Yang Y, Zhou Q, Weiss JM, Howard OZ, McPherson JM, Wakefield LM, Oppenheim JJ. Chen X, et al. PLoS One. 2014 Jan 9;9(1):e85398. doi: 10.1371/journal.pone.0085398. eCollection 2014. PLoS One. 2014. PMID: 24416401 Free PMC article.

4

Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis.

Yang Y, Yang HH, Hu Y, Watson PH, Liu H, Geiger TR, Anver MR, Haines DC, Martin P, Green JE, Lee MP, Hunter KW, Wakefield LM. Yang Y, et al. Oncotarget. 2017 May 9;8(19):30621-30643. doi: 10.18632/oncotarget.15695. Oncotarget. 2017. PMID: 28430642 Free PMC article.

5

The Outcome of TGFβ Antagonism in Metastatic Breast Cancer Models In Vivo Reflects a Complex Balance between Tumor-Suppressive and Proprogression Activities of TGFβ.

Yang Y, Yang HH, Tang B, Wu AML, Flanders KC, Moshkovich N, Weinberg DS, Welsh MA, Weng J, Ochoa HJ, Hu TY, Herrmann MA, Chen J, Edmondson EF, Simpson RM, Liu F, Liu H, Lee MP, Wakefield LM. Yang Y, et al. Clin Cancer Res. 2020 Feb 1;26(3):643-656. doi: 10.1158/1078-0432.CCR-19-2370. Epub 2019 Oct 3. Clin Cancer Res. 2020. PMID: 31582516 Free PMC article.

6

Smad3 in the mammary epithelium has a nonredundant role in the induction of apoptosis, but not in the regulation of proliferation or differentiation by transforming growth factor-beta.

Yang YA, Tang B, Robinson G, Hennighausen L, Brodie SG, Deng CX, Wakefield LM. Yang YA, et al. Cell Growth Differ. 2002 Mar;13(3):123-30. Cell Growth Differ. 2002. PMID: 11959813

7

Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects.

Yang YA, Dukhanina O, Tang B, Mamura M, Letterio JJ, MacGregor J, Patel SC, Khozin S, Liu ZY, Green J, Anver MR, Merlino G, Wakefield LM. Yang YA, et al. J Clin Invest. 2002 Jun;109(12):1607-15. doi: 10.1172/JCI15333. J Clin Invest. 2002. PMID: 12070308 Free PMC article.

8

A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland.

Kohn EA, Du Z, Sato M, Van Schyndle CM, Welsh MA, Yang YA, Stuelten CH, Tang B, Ju W, Bottinger EP, Wakefield LM. Kohn EA, et al. Among authors: yang ya. Breast Cancer Res. 2010;12(5):R83. doi: 10.1186/bcr2728. Epub 2010 Oct 13. Breast Cancer Res. 2010. PMID: 20942910 Free PMC article.

9

Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model.

Sato M, Matsubara T, Adachi J, Hashimoto Y, Fukamizu K, Kishida M, Yang YA, Wakefield LM, Tomonaga T. Sato M, et al. Among authors: yang ya. PLoS One. 2015 May 18;10(5):e0126483. doi: 10.1371/journal.pone.0126483. eCollection 2015. PLoS One. 2015. PMID: 25993439 Free PMC article.

10

Transforming growth factor-beta and breast cancer: Lessons learned from genetically altered mouse models.

Wakefield LM, Yang YA, Dukhanina O. Wakefield LM, et al. Among authors: yang ya. Breast Cancer Res. 2000;2(2):100-6. doi: 10.1186/bcr41. Epub 2000 Feb 21. Breast Cancer Res. 2000. PMID: 11250699 Free PMC article. Review.

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