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Page 1
An outlook on using serial femtosecond crystallography in drug discovery.
Mishin A, Gusach A, Luginina A, Marin E, Borshchevskiy V, Cherezov V. Mishin A, et al. Expert Opin Drug Discov. 2019 Sep;14(9):933-945. doi: 10.1080/17460441.2019.1626822. Epub 2019 Jun 11. Expert Opin Drug Discov. 2019. PMID: 31184514 Free PMC article. Review.
Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
Luginina A, Gusach A, Marin E, Mishin A, Brouillette R, Popov P, Shiriaeva A, Besserer-Offroy É, Longpré JM, Lyapina E, Ishchenko A, Patel N, Polovinkin V, Safronova N, Bogorodskiy A, Edelweiss E, Hu H, Weierstall U, Liu W, Batyuk A, Gordeliy V, Han GW, Sarret P, Katritch V, Borshchevskiy V, Cherezov V. Luginina A, et al. Sci Adv. 2019 Oct 9;5(10):eaax2518. doi: 10.1126/sciadv.aax2518. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31633023 Free PMC article.
Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors.
Gusach A, Luginina A, Marin E, Brouillette RL, Besserer-Offroy É, Longpré JM, Ishchenko A, Popov P, Patel N, Fujimoto T, Maruyama T, Stauch B, Ergasheva M, Romanovskaia D, Stepko A, Kovalev K, Shevtsov M, Gordeliy V, Han GW, Katritch V, Borshchevskiy V, Sarret P, Mishin A, Cherezov V. Gusach A, et al. Nat Commun. 2019 Dec 6;10(1):5573. doi: 10.1038/s41467-019-13348-2. Nat Commun. 2019. PMID: 31811124 Free PMC article.
Beyond structure: emerging approaches to study GPCR dynamics.
Gusach A, Maslov I, Luginina A, Borshchevskiy V, Mishin A, Cherezov V. Gusach A, et al. Curr Opin Struct Biol. 2020 Aug;63:18-25. doi: 10.1016/j.sbi.2020.03.004. Epub 2020 Apr 16. Curr Opin Struct Biol. 2020. PMID: 32305785 Review.
Metabolic Fate of Human Immunoactive Sterols in Mycobacterium tuberculosis.
Varaksa T, Bukhdruker S, Grabovec I, Marin E, Kavaleuski A, Gusach A, Kovalev K, Maslov I, Luginina A, Zabelskii D, Astashkin R, Shevtsov M, Smolskaya S, Kavaleuskaya A, Shabunya P, Baranovsky A, Dolgopalets V, Charnou Y, Savachka A, Litvinovskaya R, Hurski A, Shevchenko E, Rogachev A, Mishin A, Gordeliy V, Gabrielian A, Hurt DE, Nikonenko B, Majorov K, Apt A, Rosenthal A, Gilep A, Borshchevskiy V, Strushkevich N. Varaksa T, et al. J Mol Biol. 2021 Feb 19;433(4):166763. doi: 10.1016/j.jmb.2020.166763. Epub 2020 Dec 24. J Mol Biol. 2021. PMID: 33359098
19 results