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Regulation of cathepsin D activity by the FTLD protein progranulin.
Zhou X, Paushter DH, Feng T, Pardon CM, Mendoza CS, Hu F. Zhou X, et al. Acta Neuropathol. 2017 Jul;134(1):151-153. doi: 10.1007/s00401-017-1719-5. Epub 2017 May 10. Acta Neuropathol. 2017. PMID: 28493053 Free PMC article. No abstract available.
Lysosomal processing of progranulin.
Zhou X, Paushter DH, Feng T, Sun L, Reinheckel T, Hu F. Zhou X, et al. Mol Neurodegener. 2017 Aug 23;12(1):62. doi: 10.1186/s13024-017-0205-9. Mol Neurodegener. 2017. PMID: 28835281 Free PMC article.
Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity.
Nicholson AM, Zhou X, Perkerson RB, Parsons TM, Chew J, Brooks M, DeJesus-Hernandez M, Finch NA, Matchett BJ, Kurti A, Jansen-West KR, Perkerson E, Daughrity L, Castanedes-Casey M, Rousseau L, Phillips V, Hu F, Gendron TF, Murray ME, Dickson DW, Fryer JD, Petrucelli L, Rademakers R. Nicholson AM, et al. Among authors: zhou x. Acta Neuropathol Commun. 2018 May 31;6(1):42. doi: 10.1186/s40478-018-0545-x. Acta Neuropathol Commun. 2018. PMID: 29855382 Free PMC article.
Progranulin deficiency leads to reduced glucocerebrosidase activity.
Zhou X, Paushter DH, Pagan MD, Kim D, Nunez Santos M, Lieberman RL, Overkleeft HS, Sun Y, Smolka MB, Hu F. Zhou X, et al. PLoS One. 2019 Jul 10;14(7):e0212382. doi: 10.1371/journal.pone.0212382. eCollection 2019. PLoS One. 2019. PMID: 31291241 Free PMC article.
53,179 results
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