Hu F - Search Results

1

The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway.

Sullivan PM, Zhou X, Robins AM, Paushter DH, Kim D, Smolka MB, Hu F. Sullivan PM, et al. Among authors: hu f. Acta Neuropathol Commun. 2016 May 18;4(1):51. doi: 10.1186/s40478-016-0324-5. Acta Neuropathol Commun. 2016. PMID: 27193190 Free PMC article.

2

The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function.

Brady OA, Zheng Y, Murphy K, Huang M, Hu F. Brady OA, et al. Among authors: hu f. Hum Mol Genet. 2013 Feb 15;22(4):685-95. doi: 10.1093/hmg/dds475. Epub 2012 Nov 6. Hum Mol Genet. 2013. PMID: 23136129 Free PMC article.

3

Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain.

Busch JI, Martinez-Lage M, Ashbridge E, Grossman M, Van Deerlin VM, Hu F, Lee VM, Trojanowski JQ, Chen-Plotkin AS. Busch JI, et al. Among authors: hu f. Acta Neuropathol Commun. 2013 Jul 11;1:36. doi: 10.1186/2051-5960-1-36. Acta Neuropathol Commun. 2013. PMID: 24252750 Free PMC article.

4

Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).

Brady OA, Zhou X, Hu F. Brady OA, et al. Among authors: hu f. J Biol Chem. 2014 Jul 11;289(28):19670-80. doi: 10.1074/jbc.M113.515700. Epub 2014 May 28. J Biol Chem. 2014. PMID: 24872421 Free PMC article.

5

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.

Zhou X, Sun L, Bastos de Oliveira F, Qi X, Brown WJ, Smolka MB, Sun Y, Hu F. Zhou X, et al. Among authors: hu f. J Cell Biol. 2015 Sep 14;210(6):991-1002. doi: 10.1083/jcb.201502029. J Cell Biol. 2015. PMID: 26370502 Free PMC article.

6

Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiency.

Zhou X, Sun L, Brady OA, Murphy KA, Hu F. Zhou X, et al. Among authors: hu f. Acta Neuropathol Commun. 2017 Jan 26;5(1):9. doi: 10.1186/s40478-017-0412-1. Acta Neuropathol Commun. 2017. PMID: 28126008 Free PMC article.

7

Regulation of cathepsin D activity by the FTLD protein progranulin.

Zhou X, Paushter DH, Feng T, Pardon CM, Mendoza CS, Hu F. Zhou X, et al. Among authors: hu f. Acta Neuropathol. 2017 Jul;134(1):151-153. doi: 10.1007/s00401-017-1719-5. Epub 2017 May 10. Acta Neuropathol. 2017. PMID: 28493053 Free PMC article. No abstract available.

8

Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations.

Zhou X, Sun L, Bracko O, Choi JW, Jia Y, Nana AL, Brady OA, Hernandez JCC, Nishimura N, Seeley WW, Hu F. Zhou X, et al. Among authors: hu f. Nat Commun. 2017 May 25;8:15277. doi: 10.1038/ncomms15277. Nat Commun. 2017. PMID: 28541286 Free PMC article.

9

The interaction between progranulin and prosaposin is mediated by granulins and the linker region between saposin B and C.

Zhou X, Sullivan PM, Sun L, Hu F. Zhou X, et al. Among authors: hu f. J Neurochem. 2017 Oct;143(2):236-243. doi: 10.1111/jnc.14110. Epub 2017 Aug 4. J Neurochem. 2017. PMID: 28640985 Free PMC article.

10

Lysosomal processing of progranulin.

Zhou X, Paushter DH, Feng T, Sun L, Reinheckel T, Hu F. Zhou X, et al. Among authors: hu f. Mol Neurodegener. 2017 Aug 23;12(1):62. doi: 10.1186/s13024-017-0205-9. Mol Neurodegener. 2017. PMID: 28835281 Free PMC article.

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