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Angst MS, Fragiadakis GK, Gaudillière B, Aghaeepour N, Nolan GP. Angst MS, et al. Among authors: fragiadakis gk. Anesthesiology. 2016 Jun;124(6):1414-5. doi: 10.1097/ALN.0000000000001091. Anesthesiology. 2016. PMID: 27187126 Free PMC article. No abstract available.
A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling.
Hackney JA, Shivram H, Vander Heiden J, Overall C, Orozco L, Gao X, Kim E, West N, Qamra A, Chang D, Chakrabarti A, Choy DF, Combes AJ, Courau T, Fragiadakis GK, Rao AA, Ray A, Tsui J, Hu K, Kuhn NF, Krummel MF, Erle DJ, Kangelaris K, Sarma A, Lyon Z, Calfee CS, Woodruff PG, Ghale R, Mick E, Byrne A, Zha BS, Langelier C, Hendrickson CM, van der Wijst MGP, Hartoularos GC, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Ye CJ; UCSF COMET Consortium; Ramalingam T, McBride JM, Cai F, Teterina A, Bao M, Tsai L, Rosas IO, Regev A, Kapadia SB, Bauer RN, Rosenberger CM. Hackney JA, et al. Among authors: fragiadakis gk. iScience. 2023 Sep 1;26(10):107813. doi: 10.1016/j.isci.2023.107813. eCollection 2023 Oct 20. iScience. 2023. PMID: 37810211 Free PMC article.
Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19.
Neyton LPA, Patel RK, Sarma A; UCSF COMET Consortium; Willmore A, Haller SC, Kangelaris KN, Eckalbar WL, Erle DJ, Krummel MF, Hendrickson CM, Woodruff PG, Langelier CR, Calfee CS, Fragiadakis GK. Neyton LPA, et al. Among authors: fragiadakis gk. Nat Commun. 2024 Jun 28;15(1):5483. doi: 10.1038/s41467-024-49756-2. Nat Commun. 2024. PMID: 38942804 Free PMC article.
Single-cell RNA-Seq analysis reveals cell subsets and gene signatures associated with rheumatoid arthritis disease activity.
Binvignat M, Miao BY, Wibrand C, Yang MM, Rychkov D, Flynn E, Nititham J, Tamaki W, Khan U, Carvidi A, Krueger M, Niemi E, Sun Y, Fragiadakis GK, Sellam J, Mariotti-Ferrandiz E, Klatzmann D, Gross AJ, Ye CJ, Butte AJ, Criswell LA, Nakamura MC, Sirota M. Binvignat M, et al. Among authors: fragiadakis gk. JCI Insight. 2024 Jul 2;9(16):e178499. doi: 10.1172/jci.insight.178499. JCI Insight. 2024. PMID: 38954480 Free PMC article.
Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants.
Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Network I, Haddad EK, Reed EF, Kraft M, McComsey GA, Metcalf J, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar W, Maecker H, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Augustine AD, Sekaly RP, Ehrlich LIR, Fourati S, Peters B, Kleinstein SH, Guan L. Gygi JP, et al. Among authors: fragiadakis gk. bioRxiv [Preprint]. 2023 Nov 6:2023.11.03.565292. doi: 10.1101/2023.11.03.565292. bioRxiv. 2023. Update in: J Clin Invest. 2024 May 1;134(9):e176640. doi: 10.1172/JCI176640 PMID: 37986828 Free PMC article. Updated. Preprint.
Single-cell and spatial multi-omics highlight effects of anti-integrin therapy across cellular compartments in ulcerative colitis.
Mennillo E, Kim YJ, Lee G, Rusu I, Patel RK, Dorman LC, Flynn E, Li S, Bain JL, Andersen C, Rao A, Tamaki S, Tsui J, Shen A, Lotstein ML, Rahim M, Naser M, Bernard-Vazquez F, Eckalbar W, Cho SJ, Beck K, El-Nachef N, Lewin S, Selvig DR, Terdiman JP, Mahadevan U, Oh DY, Fragiadakis GK, Pisco A, Combes AJ, Kattah MG. Mennillo E, et al. Among authors: fragiadakis gk. Nat Commun. 2024 Feb 19;15(1):1493. doi: 10.1038/s41467-024-45665-6. Nat Commun. 2024. PMID: 38374043 Free PMC article.
Microbial dynamics and pulmonary immune responses in COVID-19 secondary bacterial pneumonia.
Spottiswoode N, Tsitsiklis A, Chu VT, Phan HV, DeVoe C, Love C, Ghale R, Bloomstein J, Zha BS, Maguire CP, Glascock A, Sarma A, Mourani PM, Kalantar KL, Detweiler A, Neff N, Haller SC; COMET Consortium; DeRisi JL, Erle DJ, Hendrickson CM, Kangelaris KN, Krummel MF, Matthay MA, Woodruff PG, Calfee CS, Langelier CR. Spottiswoode N, et al. Nat Commun. 2024 Oct 29;15(1):9339. doi: 10.1038/s41467-024-53566-x. Nat Commun. 2024. PMID: 39472555 Free PMC article.
Clinical recovery from surgery correlates with single-cell immune signatures.
Gaudillière B, Fragiadakis GK, Bruggner RV, Nicolau M, Finck R, Tingle M, Silva J, Ganio EA, Yeh CG, Maloney WJ, Huddleston JI, Goodman SB, Davis MM, Bendall SC, Fantl WJ, Angst MS, Nolan GP. Gaudillière B, et al. Among authors: fragiadakis gk. Sci Transl Med. 2014 Sep 24;6(255):255ra131. doi: 10.1126/scitranslmed.3009701. Sci Transl Med. 2014. PMID: 25253674 Free PMC article.
67 results