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SYNBIOCHEM-a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals.
Carbonell P, Currin A, Dunstan M, Fellows D, Jervis A, Rattray NJ, Robinson CJ, Swainston N, Vinaixa M, Williams A, Yan C, Barran P, Breitling R, Chen GG, Faulon JL, Goble C, Goodacre R, Kell DB, Feuvre RL, Micklefield J, Scrutton NS, Shapira P, Takano E, Turner NJ. Carbonell P, et al. Biochem Soc Trans. 2016 Jun 15;44(3):675-7. doi: 10.1042/BST20160009. Biochem Soc Trans. 2016. PMID: 27284023 Free PMC article.
An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals.
Carbonell P, Jervis AJ, Robinson CJ, Yan C, Dunstan M, Swainston N, Vinaixa M, Hollywood KA, Currin A, Rattray NJW, Taylor S, Spiess R, Sung R, Williams AR, Fellows D, Stanford NJ, Mulherin P, Le Feuvre R, Barran P, Goodacre R, Turner NJ, Goble C, Chen GG, Kell DB, Micklefield J, Breitling R, Takano E, Faulon JL, Scrutton NS. Carbonell P, et al. Among authors: jervis aj. Commun Biol. 2018 Jun 8;1:66. doi: 10.1038/s42003-018-0076-9. eCollection 2018. Commun Biol. 2018. PMID: 30271948 Free PMC article.
Machine Learning of Designed Translational Control Allows Predictive Pathway Optimization in Escherichia coli.
Jervis AJ, Carbonell P, Vinaixa M, Dunstan MS, Hollywood KA, Robinson CJ, Rattray NJW, Yan C, Swainston N, Currin A, Sung R, Toogood H, Taylor S, Faulon JL, Breitling R, Takano E, Scrutton NS. Jervis AJ, et al. ACS Synth Biol. 2019 Jan 18;8(1):127-136. doi: 10.1021/acssynbio.8b00398. Epub 2019 Jan 7. ACS Synth Biol. 2019. PMID: 30563328 Free article.
Towards synthesis of monoterpenes and derivatives using synthetic biology.
Zebec Z, Wilkes J, Jervis AJ, Scrutton NS, Takano E, Breitling R. Zebec Z, et al. Among authors: jervis aj. Curr Opin Chem Biol. 2016 Oct;34:37-43. doi: 10.1016/j.cbpa.2016.06.002. Epub 2016 Jun 14. Curr Opin Chem Biol. 2016. PMID: 27315341 Free article. Review.
Highly multiplexed, fast and accurate nanopore sequencing for verification of synthetic DNA constructs and sequence libraries.
Currin A, Swainston N, Dunstan MS, Jervis AJ, Mulherin P, Robinson CJ, Taylor S, Carbonell P, Hollywood KA, Yan C, Takano E, Scrutton NS, Breitling R. Currin A, et al. Among authors: jervis aj. Synth Biol (Oxf). 2019 Oct 29;4(1):ysz025. doi: 10.1093/synbio/ysz025. eCollection 2019. Synth Biol (Oxf). 2019. PMID: 32995546 Free PMC article.
Rapid prototyping of microbial production strains for the biomanufacture of potential materials monomers.
Robinson CJ, Carbonell P, Jervis AJ, Yan C, Hollywood KA, Dunstan MS, Currin A, Swainston N, Spiess R, Taylor S, Mulherin P, Parker S, Rowe W, Matthews NE, Malone KJ, Le Feuvre R, Shapira P, Barran P, Turner NJ, Micklefield J, Breitling R, Takano E, Scrutton NS. Robinson CJ, et al. Among authors: jervis aj. Metab Eng. 2020 Jul;60:168-182. doi: 10.1016/j.ymben.2020.04.008. Epub 2020 Apr 23. Metab Eng. 2020. PMID: 32335188 Free PMC article.
32 results