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Page 1
Further optimization of the M1 PAM VU0453595: Discovery of novel heterobicyclic core motifs with improved CNS penetration.
Panarese JD, Cho HP, Adams JJ, Nance KD, Garcia-Barrantes PM, Chang S, Morrison RD, Blobaum AL, Niswender CM, Stauffer SR, Conn PJ, Lindsley CW. Panarese JD, et al. Among authors: niswender cm. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3822-5. doi: 10.1016/j.bmcl.2016.04.083. Epub 2016 Apr 29. Bioorg Med Chem Lett. 2016. PMID: 27173801 Free PMC article.
mGluR7's lucky number.
Conn PJ, Niswender CM. Conn PJ, et al. Among authors: niswender cm. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):251-2. doi: 10.1073/pnas.0510051103. Epub 2006 Jan 3. Proc Natl Acad Sci U S A. 2006. PMID: 16407154 Free PMC article. No abstract available.
An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission.
Shirey JK, Xiang Z, Orton D, Brady AE, Johnson KA, Williams R, Ayala JE, Rodriguez AL, Wess J, Weaver D, Niswender CM, Conn PJ. Shirey JK, et al. Among authors: niswender cm. Nat Chem Biol. 2008 Jan;4(1):42-50. doi: 10.1038/nchembio.2007.55. Epub 2007 Dec 2. Nat Chem Biol. 2008. PMID: 18059262
Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4.
Niswender CM, Johnson KA, Weaver CD, Jones CK, Xiang Z, Luo Q, Rodriguez AL, Marlo JE, de Paulis T, Thompson AD, Days EL, Nalywajko T, Austin CA, Williams MB, Ayala JE, Williams R, Lindsley CW, Conn PJ. Niswender CM, et al. Mol Pharmacol. 2008 Nov;74(5):1345-58. doi: 10.1124/mol.108.049551. Epub 2008 Jul 29. Mol Pharmacol. 2008. PMID: 18664603 Free PMC article.
269 results