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Inhibition of transmitter release and attenuation of anti-retroviral-associated and tibial nerve injury-related painful peripheral neuropathy by novel synthetic Ca2+ channel peptides.
Wilson SM, Schmutzler BS, Brittain JM, Dustrude ET, Ripsch MS, Pellman JJ, Yeum TS, Hurley JH, Hingtgen CM, White FA, Khanna R. Wilson SM, et al. Among authors: khanna r. J Biol Chem. 2012 Oct 12;287(42):35065-35077. doi: 10.1074/jbc.M112.378695. Epub 2012 Aug 13. J Biol Chem. 2012. PMID: 22891239 Free PMC article.
S., Wang, Y., Fehrenbacher, J. C., Fitz, S. D., Khanna, M., Park, C. K., Schmutzler, B. S., Cheon, B. M., Due, M. R., Brustovetsky, T., Ashpole, N. ...A., and Khanna, R. (2011) Suppression of inflammatory and neuropathic pain by uncoupling CRMP2 from t …
S., Wang, Y., Fehrenbacher, J. C., Fitz, S. D., Khanna, M., Park, C. K., Schmutzler, B. S., Cheon, B. M., Due, M. R., Brustove …
CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking.
Dustrude ET, Wilson SM, Ju W, Xiao Y, Khanna R. Dustrude ET, et al. Among authors: khanna r. J Biol Chem. 2013 Aug 23;288(34):24316-31. doi: 10.1074/jbc.M113.474924. Epub 2013 Jul 8. J Biol Chem. 2013. PMID: 23836888 Free PMC article.
Substituted N-(biphenyl-4'-yl)methyl (R)-2-acetamido-3-methoxypropionamides: potent anticonvulsants that affect frequency (use) dependence and slow inactivation of sodium channels.
Lee H, Park KD, Torregrosa R, Yang XF, Dustrude ET, Wang Y, Wilson SM, Barbosa C, Xiao Y, Cummins TR, Khanna R, Kohn H. Lee H, et al. Among authors: khanna r. J Med Chem. 2014 Jul 24;57(14):6165-82. doi: 10.1021/jm500707r. Epub 2014 Jul 15. J Med Chem. 2014. PMID: 25004277 Free PMC article.
The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth.
Wilson SM, Moutal A, Melemedjian OK, Wang Y, Ju W, François-Moutal L, Khanna M, Khanna R. Wilson SM, et al. Among authors: khanna r, khanna m. Front Cell Neurosci. 2014 Jul 24;8:196. doi: 10.3389/fncel.2014.00196. eCollection 2014. Front Cell Neurosci. 2014. PMID: 25104922 Free PMC article.
Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lacosamide and safinamide.
Park KD, Yang XF, Dustrude ET, Wang Y, Ripsch MS, White FA, Khanna R, Kohn H. Park KD, et al. Among authors: khanna r. ACS Chem Neurosci. 2015 Feb 18;6(2):316-30. doi: 10.1021/cn5002182. Epub 2014 Dec 9. ACS Chem Neurosci. 2015. PMID: 25418676 Free PMC article.
2,139 results